Psychological Distress Impairs Clearance of Psoriasis in Patients Treated With Photochemotherapy

Fortune, Dónal G.; Richards, Helen L.; Kirby, Brian; McElhone, Kathleen; Markham, Trevor; Rogers, S.; Main, Chris J.; Griffiths, C.E.M.

doi:10.1001/archderm.139.6.752

Cited by 211 publications

(189 citation statements)

References 39 publications

(38 reference statements)

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“…This could be because of their experience of quite a number of relapses, their knowledge of nature of the illness, and poorer adaptation of living with the illness. This finding was in relation to the finding of Tee et al 22 where there was no significant correlation seen between anxiety and depression scores vs duration of psoriasis. A study by Lakshmy et al 21 showed a significant association between severity and duration of psoriasis and psychological distress (Perceived Stress Scale score).…”

Section: Discussionsupporting

confidence: 83%

“…Age showed no significant association with anxiety and depression. 21 However, a study by Fortune et al 22 showed that female patients appear to be more susceptible to depression than male patients. Although there was no statistically significant association of duration of illness with anxiety score, depression score, or QOL score in psoriasis cases with GHQ score ≥3, more anxiety and perceived impairment of QOL was experienced by patients with duration of illness of 1 to 5 years.…”

Section: Discussionmentioning

confidence: 99%

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Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital

Kumar¹,

Shrivastava²,

Jaiswal³

et al. 2017

International Journal of Advanced and Integrated Medical Sciences

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Introduction: Psoriasis is an inflammatory skin disease, which may be persistent, disfiguring, and stigmatizing. The disease is frequent, with prevalence estimates ranging from 0.3 to 2.5%. It is characterized by thick, red, scaly lesion that may appear on any part of the body. Psoriasis is associated with significant psychological and psychiatric morbidity, experience of stigmatization, and decreased health-related quality of life (QOL).

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital

Kumar¹,

Shrivastava²,

Jaiswal³

et al. 2017

International Journal of Advanced and Integrated Medical Sciences

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show abstract

“…Particularly in patients with psoriasis, it has been observed that psychological distress results in an unfavorable outcome in the response to PUVA. 7 Adding cognitive behavior therapy to standard treatment improved the clinical severity of psoriasis. 8 Given our findings and the literature on psoriasis, additional research is needed in this area, because it is likely that psychological distress affects the outcomes of patients with CTCL, possibly in a similar manner to that observed in patients with psoriasis.…”

Section: Discussionmentioning

confidence: 99%

Significant impact of cutaneous T‐cell lymphoma on patients' quality of life

Demierre

Gan

Jones

et al. 2006

Cancer

152

141

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BACKGROUND.Cutaneous T‐cell lymphoma (CTCL) can have a profound impact on a patient's health‐related quality of life; however, little is known about its actual impact. The authors evaluated patients' perspectives on the impact of CTCL on physical functioning, lifestyle, emotional well being, and satisfaction with treatment.METHODS.A 4‐page, self‐administered questionnaire was mailed and made available online in March 2005 to the entire United States membership of the Mycosis Fungoides Foundation (n = 930 members). Outcome measures were patients' perspectives on the psychosocial impact of CTCL and the management of their disease.RESULTS.The response rate was 68%, and 93.6% of respondents were white. The majority of respondents had mycosis fungoides (89%). Respondents were bothered by skin redness (94%) and by the extent of symptoms that affected their choice of clothing (63%). For most patients, the disease had a functional impact, rendering them tired or affecting their sleep. Health distress was reported by almost all respondents, with 94% reporting that they worried about the seriousness of their disease and 80% worrying about dying from the disease. Sixty‐two percent of respondents reported that their disease made them feel unattractive, 85% reported that their treatment made their disease seem more manageable, but 61% reported that they felt burdened financially by their disease.CONCLUSIONS.The high response rate and patients' responses to the survey provided compelling evidence that patients believed CTCL had a profound and severe impact on their functioning, emotional, and social well being. A striking health distress was prevalent in almost all respondents. Although the majority of patients reported that treatments made their disease more manageable, a significant proportion reported that they felt burdened financially by their disease. Cancer 2006. © 2006 American Cancer Society.

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“…The importance of stress in psoriasis has been further highlighted, since psychological distress affects treatment outcome in psoriatic patients. For instance, the level of stress may prolong the time taken for psoralen plus UVA (PUVA) to clear the symptoms of psoriasis (Fortune, Richards et al 2003). Accordingly, stress reduction by stress management, relaxation or cognitive techniques shortened the time to clear psoriasis symptoms by PUVA, and, moreover, improved the clinical severity of psoriasis (Kabat-Zinn, Wheeler et al 1998;Fortune, Richards et al 2002).…”

Section: Psoriasis Psychosocial Aspectsmentioning

confidence: 99%

“…Psychological sequelae of the disease can impair the response to treatment, since patients with pathological levels of anxiety are less likely to respond to therapy (Fortune, Richards et al 2003). Thus, stress in the form of pathological worry has a deleterious effect on response to therapy.…”

Section: Psoriasis Psychosocial Aspectsmentioning

confidence: 99%

Psoriasis: Epidemiology, Clinical and Histological Features, Triggering Factors, Assessment of Severity and Psychosocial Aspects

Coimbra¹,

Oliveira²,

Figueiredo³

et al. 2012

Psoriasis - A Systemic Disease

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Psychological Distress Impairs Clearance of Psoriasis in Patients Treated With Photochemotherapy

Cited by 211 publications

References 39 publications

Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital

Psychiatric Morbidity and Quality of Life in Patients suffering from Psoriasis in a Tertiary Care Hospital

Significant impact of cutaneous T‐cell lymphoma on patients' quality of life

Psoriasis: Epidemiology, Clinical and Histological Features, Triggering Factors, Assessment of Severity and Psychosocial Aspects

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