1966
DOI: 10.1001/archpsyc.1966.01730170051008
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Psycho-Endocrine Effects of Perceptual and Social Isolation

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Cited by 16 publications

(7 citation statements)
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“…Some evidence of greater arousal in the SD condition was found with hormone measures of adrenal response (17-KGS and 17-KS) and anterior pituitary response (thyroid-stimulating hormone), as well as greater increases in the anxiety measure on the AACL. However, the latest study, 25 in which the 2 sessions were extended to 24 hr. and subjects also collected urine samples on an unconfined day, is leading us to the conclusion that the hormone arousal effects are as much a function of the general conditions of social isolation and confinement as of the sensory deprivation.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Some evidence of greater arousal in the SD condition was found with hormone measures of adrenal response (17-KGS and 17-KS) and anterior pituitary response (thyroid-stimulating hormone), as well as greater increases in the anxiety measure on the AACL. However, the latest study, 25 in which the 2 sessions were extended to 24 hr. and subjects also collected urine samples on an unconfined day, is leading us to the conclusion that the hormone arousal effects are as much a function of the general conditions of social isolation and confinement as of the sensory deprivation.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…This mechanism as an alternative to or combined with the process of habituation, may explain the gradual decline in psychoendocrine response on repeated stimulation (cf. Rasmus, 1936137;Persky et al, 1966;Pekkarinen et al, 1960), as well as the relatively low adrenal hormone levels found in soldiers exposed to prolonged combat action (Pace et al, 1956;Bourne, 1969 and and in chronically anxious patients (Levi, unpublished results).…”
Section: Stimulus Duration and Timing Of Measurementsmentioning
confidence: 97%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…For example, subjects placed in an isolation chamber were highly motivated to seek changes in the setting. Persky, Zuckerman, Basu, and Thornton (1966) reported that subjects under these conditions kept a television set on continuously except when sleeping.…”
Section: Simulating Views Out Of Confined Settingsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.