“…The risk factors for depression in SLE are not adequately understood 4,5,6,7,8,10,11,12,13,14,15,16,17,18,19,20,21,22,23 . SLE activity 7,10,13 , other neuropsychiatric manifestations 3,8,15,17 , or autoantibodies such as anticardiolipin (aCL) or anti-P lupus antibody 12,16 could directly predispose to depression.…”