2010
DOI: 10.1007/s00296-010-1689-6
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Abstract: Physicians’ awareness about neuropsychiatric syndromes in systemic lupus erythematosus (SLE) is not rarely limited to seizures and psychoses included in the American College of Rheumatology (ACR) classification. Involvement of the central nervous system (CNS) with its rich symptomatology still belongs to the faintly recognised and understood aspects of lupus. The objective was to investigate prevalence and clinical correlations of psychiatric disorders in SLE patients. Fifty-two SLE patients were included. Dis… Show more

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Cited by 44 publications
(29 citation statements)
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“…This constant experiencing of SLE makes patients experts on their disease [1,3,17]. Indeed, studies revealed that a longer experience of SLE often results in empowerment and less concern and anxiety suggesting an adaptation process [1,12,18]. Students not having SLE had no need to adapt to the illness and create strategies to face the symptoms.…”
Section: Discussionmentioning
confidence: 95%
“…This constant experiencing of SLE makes patients experts on their disease [1,3,17]. Indeed, studies revealed that a longer experience of SLE often results in empowerment and less concern and anxiety suggesting an adaptation process [1,12,18]. Students not having SLE had no need to adapt to the illness and create strategies to face the symptoms.…”
Section: Discussionmentioning
confidence: 95%
“…Depression could also be a secondary phenomenon caused by other manifestations of the disease (for instance, pain and arthritis 19 ), by corticosteroid therapy 24 , or as an emotional reaction to the chronicity or social stress caused by having SLE 1 . The results from past studies are inconsistent, with some studies finding no association between depression and disease activity 4,6,11,18,20 , other neuropsychiatric manifestations 6 , autoantibodies [e.g., anti-P 6,20 , antiphospholipid antibodies (aPL) 23 ], or corticosteroid usage 10,18 . One previous analysis found that depression was associated with secondary Sjögren syndrome 8 .…”
mentioning
confidence: 98%
“…The risk factors for depression in SLE are not adequately understood 4,5,6,7,8,10,11,12,13,14,15,16,17,18,19,20,21,22,23 . SLE activity 7,10,13 , other neuropsychiatric manifestations 3,8,15,17 , or autoantibodies such as anticardiolipin (aCL) or anti-P lupus antibody 12,16 could directly predispose to depression.…”
mentioning
confidence: 99%
“…6,7 Recent evidence suggests that the prevalence of depression in SLE patients is between 11.5% and 47%. [8][9][10][11][12][13] In addition, a recent study suggests that severity of depression increases with more severe disease activity of SLE. 14 The extended life span of SLE patients from Dovepress submit your manuscript | www.dovepress.com current advances in medicine leads these patients to encounter a relapsing and remitting course of the disease and adverse events from several treatments that may deteriorate their quality of life and intimate relationships, and may precipitate depression.…”
Section: Introductionmentioning
confidence: 99%