Psoriatic Arthritis sine Psoriasis

“…Корреляции между тяжестью Пс и ПсА не выявлено. У большинства па-циентов (70%) Пс возникает раньше поражения суставов, у 20% одновременно с ним и у 15-20% ПсА опережает первые клинические проявления Пс [6].…”

unclassified

Psoriatic arthritis. Clinical guidelines for diagnosis and treatment

Коротаева¹,

Корсакова²,

Логинова³

et al. 2018

RJTAO

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“…These criteria for PsA include established inflammatory articular disease with a score of at least 3 points from the following features: current psoriasis (which was assigned a score of 2 points; all other features were assigned a score of 1 point), a history of psoriasis, a family history of psoriasis, dactylitis, juxta-articular new bone formation, negativity for rheumatoid factor, and nail dystrophy [4]. Using these criteria, it is possible to classify patients as having PsA even when they do not have a current, past, or family history of psoriasis [2,4,5]. These criteria are now being used in epidemiologic studies on PsA [2].…”

mentioning

confidence: 99%

Clinical experience in 115 patients with arthritis and/or enthesitis who met the classification criteria for psoriatic arthritis (CASPAR) within the last two years—Possible association with malignant disorders

Hagiwara

Suyama

Fukuda

2015

Modern Rheumatology

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Among about 400 patients with active arthritis and/or enthesitis who were referred to our department within the last two years, 140 of them were strongly suspected as having psoriatic arthritis by a comprehensive diagnostic procedure and after consulting specialists from dermatology, orthopedics, and radiodiagnostics at our institution and other institutions. Among them, 115 patients strictly met the classification criteria for psoriatic arthritis (CASPAR). Among the 115 patients, 19 patients (9 males and 10 females) had current psoriasis and 96 patients (22 males and 74 females) did not have current psoriasis. Nineteen (16.5%) of the 115 patients had developed malignant tumor before the onset of arthritis, and 4 (3.5%) developed malignant tumor after the onset of arthritis. Twenty-two of the 23 patients who developed malignancy were female and 10 patients developed breast cancer. Differential diagnoses in these 23 patients may include paraneoplastic syndrome. We consider that it is important to take into account the possibility of paraneoplastic syndrome in patients with arthritis and/or enthesitis who apparently meet the CASPAR criteria, and detailed screening and monitoring of malignant disease may be beneficial to the patients.

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“…Для ПсА не ха-рактерны половые и возрастные различия: заболевание не имеет тенденции к началу в каком-то определенном возрасте и пора-жает с одинаковой частотой как женщин, так и мужчин. Определенные трудности для диагностики возникают в 15-20% случаев ПсА, когда суставные проявления возника-ют раньше кожных симптомов [3]. Как и многие другие воспалительные ревмати-ческие заболевания, ПсА нередко сопрово-ждается системным остеопорозом (ОП).…”

unclassified