Psoriasis y síndrome metabólico

Carrascosa, Jose Carlos Ruiz; Santiago, Salvador Arias

doi:10.1016/j.piel.2009.11.002

Cited by 7 publications

(2 citation statements)

References 105 publications

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“…With these data we can conclude that our patients with Ps have a 48% increased odds of suffering TG >200 mg/dl. These results are similar to those found by different authors [1,45,46]. …”

Section: Discussionsupporting

confidence: 93%

“…Since 1987, numerous studies have been conducted to study DL in Ps [1,2,5,6,7,8,9,10,11,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46]. The results vary since they are based on heterogeneous populations, with or without associated comorbidities, and do not always take into account prescribed medications that can alter the lipid profile or liver function tests [29,30,31,32,33,34,35].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Psoriasis Vulgaris with or without Arthritis and Independent of Disease Severity or Duration Is a Risk Factor for Hypercholesterolemia

Santos‐Juanes

Coto-Segura²,

Fernández‐Vega³

et al. 2015

Dermatology

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Background: Psoriasis (Ps) has been associated with an increased incidence of cardiovascular disease. Interesting epidemiological evidence suggests associations between Ps and dyslipidemia (DL), a well-established risk factor for cardiovascular disease. Objective: This study aimed to investigate the association between Ps and multiple measurements of DL, which include levels of triglycerides (TGs), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and total cholesterol (TCh). We also studied the relationship between DL and disease duration. Methods: A prospective hospital-based study was conducted. A total of 661 Caucasian patients with chronic plaque Ps and 661 sex- and age-matched controls were enrolled. Results: Multivariate analysis showed that in psoriatic patients the odds ratio (OR) of TCh >200 mg/dl was 1.406 (95% confidence interval 1.115-1.173), the OR of LDL cholesterol >130 mg/dl was 1.375 (95% confidence interval 1.088-1.738), the OR of HDL cholesterol <40 mg/dl was 0.881 (95% confidence interval 0.599-1.297), and the OR of TGs >150 mg/dl was 1.041 (95% confidence interval 0.783-1.385). We did not find a relationship between lipid levels and disease duration. Conclusion: Based on our population Ps is associated with alterations in TCh and LDL cholesterol, but not in TGs and HDL cholesterol, when ATP III panel levels are used. These alterations are not related to disease duration.

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“…With these data we can conclude that our patients with Ps have a 48% increased odds of suffering TG >200 mg/dl. These results are similar to those found by different authors [1,45,46]. …”

Section: Discussionsupporting

confidence: 93%