1971
DOI: 10.1001/archderm.104.3.328
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Psoriasis in Japan

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Cited by 12 publications
(3 citation statements)
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“…Our observations contrast with the findings of the only other previous study on the ApoE gene in psoriasis, which reported an association with the +4075 polymorphism (Apo e2 allele) in Japanese patients 23 . This divergence may relate to the observation that there may be differences in psoriasis in Japanese patients; the disease is much less prevalent in Japan, and is usually of the late‐onset type and sporadic 32,33 . Caucasian and Japanese forms of psoriasis may be genetically distinct, as suggested by a low frequency of HLA‐Cw6 in Japanese compared with Caucasian patients with psoriasis 34,35 .…”
Section: Discussioncontrasting
confidence: 99%
“…Our observations contrast with the findings of the only other previous study on the ApoE gene in psoriasis, which reported an association with the +4075 polymorphism (Apo e2 allele) in Japanese patients 23 . This divergence may relate to the observation that there may be differences in psoriasis in Japanese patients; the disease is much less prevalent in Japan, and is usually of the late‐onset type and sporadic 32,33 . Caucasian and Japanese forms of psoriasis may be genetically distinct, as suggested by a low frequency of HLA‐Cw6 in Japanese compared with Caucasian patients with psoriasis 34,35 .…”
Section: Discussioncontrasting
confidence: 99%
“…Psoriasis is a chronic inflammatory skin disease that affects approximately 1–3% of the population in the USA and Europe 1 . In contrast, the prevalence of this disease in Japan is very low (0.025%) 2 . Various phototherapeutic strategies, including psoralen and ultraviolet A (PUVA) therapy and narrow‐band ultraviolet B (NB‐UVB: 310–12 nm) therapy, have been widely used and shown to be highly effective in the treatment of psoriasis 3–5 .…”
Section: Introductionmentioning
confidence: 99%
“…Based upon age of onset curves, it has been proposed that there are two types of psoriasis vulgaris, early onset and late onset psoriasis, and many distictive features support this classification (2). Psoriasis affects approximately 2% of people in northern European and North American white populations, but it is relatively infrequent, even rare, among blacks, Japanese and na-tive North and South Americans (3)(4)(5). These epidemiologic data suggest that there might be genetic differences in psoriasis between Asians and Caucasians.…”
Section: Introductionmentioning
confidence: 99%