Psoriasis and the Risk of Diabetes and Hypertension

Psoriasis and type 2 diabetes risk among psoriatic patients in a Spanish population

“…We also found a higher prevalence of DM2 in patients with PsA. Our study supports previous reports, and the risk of DM2 in our population was consistent with the risk observed in previous cross‐sectional, case–control and prospective studies, with an increased risk of 1.20–2.80 8–10,12,16 . In our study population, this association was higher in late‐onset, sporadic and severe psoriasis and patients suffering from PsA.…”

Traditional and Non-traditional Cardiovascular Risk Factors and Cardiovascular Disease in Women with Psoriasis

“…Obesity is closely linked to type 2 diabetes mellitus ( 36 ) and physical activity ( 37 ). The high frequency of type 2 diabetes mellitus among women with hospital-diagnosed psoriasis seen in the current study is also consistent with previous studies ( 20 , 38 ). We also find that women with hospital-diagnosed psoriasis exercise much less than women without hospital-diagnosed psoriasis, and as a previous study of 116,430 US women found that vigorous physical activity was associated with reduced risk of incident psoriasis ( 39 ), the current results support the hypothesis that prevention of, and treatment for, obesity are a priority in women with psoriasis.…”

Psoriasis and New-Onset Diabetes

“…Additionally, very little data are available on the potential impact of psoriasis disease severity on the risk of DM, and the evidence of a relationship to psoriasis severity is sparse (5,8,38). Our results, however, are clearly in agreement with previous studies demonstrating a link between chronic inflammatory diseases, including psoriasis and rheumatoid arthritis, and augmented risk of DM (5–7,11–13,32,33,37). The increased risk of DM in patients with psoriasis is likely to contribute to the increased risk of cardiovascular morbidity and mortality observed in these patients (including the population examined in the current report), albeit this risk has been found to be increased even after adjustments for DM and other risk factors in agreement with the notion of independent effects of inflammation per se (19,20,39–41).…”