Psoríase em paciente HIV positivo

Abstract

Two patients with the acquired immunodeficiency syndrome (AIDS) developed psoriasis, one of them presenting the more severe form and the other one the milder form of the disease, were treated with zidovudine per oral via, 200mg 3 times a day. In the first case the therapeutical response was complete. No lesion was verified in the patient after 9 months under maintenance schedule. In the second case, despite the response being clear, after 6 months of treatment, the patient still presented furfuraceous scalings at limbs ever under the medication schedule.

Regressão de psoríase em paciente HIV-positivo após terapia anti-retroviral

“…Although not observed in the case reported here, these patients present a higher incidence of arthritis, reaching about 10%, 4 while among immunocompetent patients, such clinical findings only occur in 1%. Usually, the clinical forms are more serious [9][10][11] and even disfiguring, 6 with secondary complications 9,11 or exacerbation of prior disease. 12,13 Such tardive appearance of the disease without familial history or risk factors, as in the patient described here, necessitates investigation for this infec-…”

“…2 Psoriasis is a chronic dermatosis that affects approximately 1.5 to 2%3 of the world population and 1.3 to crônica que afeta cerca de 1,5 a 2% 3 da população mundial e 1,3 a 5% 3,4 dos pacientes infectados com HIV, sendo considerada sinal de mau prognóstico. 3 As apresentações clínicas podem ser mais graves, [9][10][11] até mesmo desfigurantes. 6 Destaca-se a importância de se estar atento à associação dessas doenças para que se possa realizar diagnóstico o mais precoce possível.…”

“…5% 3,4 of all patients infected with HIV and is considered to be a sign of a poor prognosis. 3 The clinical presentations can be more serious [9][10][11] and even disfiguring. 6 Hence, the importance of constant attention to an association of these pathologies in order to reach the diagnosis as early as possible.…”