Pseudopelade

Ronchese, F

doi:10.1001/archderm.1960.01580030030003

Cited by 30 publications

(14 citation statements)

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“…This entity was originally described in 1888 as a noninflammatory progressive scarring alopecia of unknown origin, characterized by patches tending to coalesce in large irregular patches with polycyclic borders [25]. Although some authors still consider it to be a separate entity, its existence as such is currently doubted by many [26,27,28,29]. Although there are multiple theories about the true nature of PB, the dermatologists that focus on the subject currently tend to consider it not as a nonspecific clinical-pathological entity, but instead, as a variant of some types of PSAs [30,31,32,33,34,35], or, alternatively, as a final atrophic stage of scarring alopecias, such as LE, LPP, or FD [36,37].…”

Section: Discussionmentioning

confidence: 99%

Primary Scarring Alopecia: Clinical-Pathological Review of 72 Cases and Review of the Literature

Villablanca

Fischer

García-García

et al. 2017

Skin Appendage Disord

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Purpose of the Study: To analyze the epidemiologic, demographic, clinical, and histological characteristics of primary scarring alopecia (PSA) cases diagnosed over a 7-year period at the Department of Dermatology, Hospital Clinic, Barcelona, Spain. Procedures: Seventy-two patients diagnosed with PSA between 2006 and 2012 were included. Age, sex, ethnic group, clinical pattern, predominant histological infiltrate, final clinical diagnosis, time of onset, treatments used, and clinical evolution were evaluated and correlated. Results: The ethnic groups were distributed as follows: 93% European-Caucasian, 5% Mestizo-American, 1% oriental, and 1% Afro-American. Most cases were females (71%), and mean age was 51 ± 6 years. The follicular pattern was the most common, and the predominant inflammatory infiltrate was lymphocytic. Lichen planopilaris and frontal fibrosing alopecia were the main diagnoses. When correlating clinical aspects and histopathology, lymphocytic PSAs had a subacute onset and resulted in a nonchanging, more stable form, while neutrophilic PSAs had a more acute onset with an evolution of acute outbreaks. PSAs in a late stage with an absent/mild infiltrate had a subclinical onset and a slowly progressive or stable evolution. Conclusions: The PSAs are severe trichological conditions. Their high clinical and histopathological variability make them a diagnostic and therapeutic challenge. Message of the Paper: Knowing the clinical and histopathological aspects of PSAs should be of crucial importance to the dermatologist.

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Section: Discussionmentioning

confidence: 99%

Primary Scarring Alopecia: Clinical-Pathological Review of 72 Cases and Review of the Literature

Villablanca

Fischer

García-García

et al. 2017

Skin Appendage Disord

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“…Many continue to maintain that pseudopelade of Brocq is distinct clinicopathologically. [173][174][175][176][177][178] Others view it as a variant of certain primary cicatricial alopecias, 66,133,[179][180][181][182] namely, lichen planopilaris and DLE, or alternatively, as the common final stage of several cicatricial alopecias (état pseudopeladique). 183,184 To confuse matters, the term pseudopelade alone is used indiscriminately in the literature to denote both pseudopelade of Brocq and other forms of cicatricial alopecia that simulate it; definition is required each time the term is used.…”

Section: Graham-little Syndromementioning

confidence: 99%

“…Brocq otherwise defined, a female predilection is reported. 10,173,180 Onset usually occurs during adulthood. 172,174,187 There are rare reports of familial disease presenting during childhood or adolescence.…”

Section: Graham-little Syndromementioning

confidence: 99%

Update on primary cicatricial alopecias

Ross

Tan

Shapiro

2005

Journal of the American Academy of Dermatology

253

323

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“…lichen planopilaris, chronic discoid lupus erythematodes, scleroderma and folliculitis decalvans. However, others [10,12,15] feel that PPB could also exist as an autonomous en tity unrelated to the above-mentioned dis eases.…”

Section: Introductionmentioning

confidence: 99%

Pseudopelade of Brocq

Braun‐Falco¹,

Imai²,

Schmoeckel³

et al. 1986

Dermatology

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41 cases with scarring alopecia seen from 1979 to 1983 were analyzed and differentiated. After exclusion of 7 cases with lichen planopilaris, of 5 cases with discoid lupus erythematosus, of 2 cases with scleroderma, and of 1 case with folliculitis decalvans, there remained 26 cases. The clinical histological and direct immunofiuorescence (DIF) findings in these patients suggest that pseudopelade of Brocq might be a distinct disease unrelated to other known types of scarring alopecia. The histopathology is characteristic, and shows the following features: little or only moderate lymphocytic infiltrate, absence of significant follicular plugging, and absence or decrease of sebaceous glands. DIF is negative, occasionally only IgM can be found at the basement membrane. The course of the disease is slowly progressive (in spite of little or no visible erythema), becoming eventually stationary after several years and resulting in a more or less severe permanent hair loss.

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Pseudopelade

Cited by 30 publications

References 0 publications

Primary Scarring Alopecia: Clinical-Pathological Review of 72 Cases and Review of the Literature

Primary Scarring Alopecia: Clinical-Pathological Review of 72 Cases and Review of the Literature

Update on primary cicatricial alopecias

Pseudopelade of Brocq

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