Pseudallescheria boydii in an immunocompromised host. Successful treatment with debridement and itraconazole

Cutaneous Scedosporium apiospermum Infection in an Immunocompromised Patient and a Review of the Literature

“…For the present, surgical debridement or drainage in addition to antifungal drugs is recommended (1,23) and this coincides with our review of the literature. BMT, bone marrow transplantation; GVHD, graft versus host disease; CRF, chronic renal failure; DIC, disseminated intravascular coagulation.…”

Cutaneous Scedosporium apiospermum infection in an immunocompromised patient.

“…In these cases the organisms typically cause acute inflammation of the dermis or subcutaneous tissues, with erythema, subcutaneous nodules, and ulcer formation. From 1980 to 1998, 18 cases of cutaneous infections caused by Scedosporium apiospermum or Pseudallescheria boydii in immunocompromised patients have been reported, [3][4][5][6][7][8][9][10][11][12][13] with the majority of cases being reported in the past four years (13 patients). [6][7][8][9][10][11][12][13] Four patients were undergoing systemic steroid treatment, and five of nine patients had leukaemia.…”

Multiple Subcutaneous Mycetomas caused by Pseudallescheria boydii: Response to therapy with oral potassium iodide solution

“…4,8 Successful treatment with itraconazole, in an immune competent pediatric patient with failure to respond to miconazole has been described. 9 Walsh et al evaluated the effect of combinations of Amphotericin B and azoles. The combinations were found to be synergistic, additive or indifferent when used for P. boydii infections.…”