Prussian blue nanocubes peroxidase mimetic-based colorimetric assay for screening acetylcholinesterase activity and its inhibitor

Ni, Pengjuan; Sun, Yujing; Dai, Haichao; Lu, Wangdong; Jiang, Shu; Wang, Yilin; Li, Zhen; Li, Zhuang

doi:10.1016/j.snb.2016.09.048

Cited by 46 publications

(24 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The detection limit can be as low as 0.16 mU mL À1 via the uorescence recovery of RhB, which was comparable to that of recently reported assays for AChE. [17][18][19] Selectivity of the assay for AChE detection…”

Section: Sensitivity Of the Assay For Ache Detectionsupporting

confidence: 80%

“…To this end, a range of methods/techniques for detection of AChE level have been employed, including the colorimetric Ellman method 8,9 or the detection of hydrogen peroxide (H 2 O 2 ) produced by oxidation of choline. 10,11 With the development of H 2 O 2 sensors, [12][13][14] recently, uorescent or colorimetric approaches based on synthetic probes and nanozymes, [15][16][17][18] as well as various electrochemical methods, 19,20 have been developed to monitor AChE activity and screen the inhibitors of AChE. However, most of these methods cannot discriminate AChE from other biothiols.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A gold nanoparticle based colorimetric and fluorescent dual-channel probe for acetylcholinesterase detection and inhibitor screening

Wang

et al. 2018

RSC Adv.

View full text Add to dashboard Cite

show abstract

Section: Sensitivity Of the Assay For Ache Detectionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

A gold nanoparticle based colorimetric and fluorescent dual-channel probe for acetylcholinesterase detection and inhibitor screening

Wang

et al. 2018

RSC Adv.

View full text Add to dashboard Cite

show abstract

“…As a matter of fact, multiple interactions between the sulfydryl group of TCh and nanozymes often coexist in a ChE-nanozyme cascade system [53,87,88]. Ni et al developed a colorimetric sensing platform for AChE activity and its inhibitor based on peroxidase-like Prussian blue nanocubes, AChE, ATCh, H 2 O 2 and TMB [87]. In their system, the generated TCh could cheat with active Fe 3+ in the nanozyme, and it also chemically reduced the product TMBox to TMB again.…”

Section: Generation Of Thiol-containing Compoundsmentioning

confidence: 99%

Nanozyme-Participated Biosensing of Pesticides and Cholinesterases: A Critical Review

Zhu

Liu

et al. 2021

Biosensors

View full text Add to dashboard Cite

To improve the output and quality of agricultural products, pesticides are globally utilized as an efficient tool to protect crops from insects. However, given that most pesticides used are difficult to decompose, they inevitably remain in agricultural products and are further enriched into food chains and ecosystems, posing great threats to human health and the environment. Thus, developing efficient methods and tools to monitor pesticide residues and related biomarkers (acetylcholinesterase and butylcholinesterase) became quite significant. With the advantages of excellent stability, tailorable catalytic performance, low cost, and easy mass production, nanomaterials with enzyme-like properties (nanozymes) are extensively utilized in fields ranging from biomedicine to environmental remediation. Especially, with the catalytic nature to offer amplified signals for highly sensitive detection, nanozymes were finding potential applications in the sensing of various analytes, including pesticides and their biomarkers. To highlight the progress in this field, here the sensing principles of pesticides and cholinesterases based on nanozyme catalysis are definitively summarized, and emerging detection methods and technologies with the participation of nanozymes are critically discussed. Importantly, typical examples are introduced to reveal the promising use of nanozymes. Also, some challenges in the field and future trends are proposed, with the hope of inspiring more efforts to advance nanozyme-involved sensors for pesticides and cholinesterases.

show abstract

“…As one of the earliest metal NPs with peroxidase activity, Fe 3 O 4 NPs have long been used in colorimetric detection [67][68][69]. In the subsequent studies, it was found that not only Fe 3 O 4 NPs, but also FeNPs and its various oxides could simulate the activity of enzymes and serve as catalysts.…”

Section: Colorimetric Detection Based On Fenpsmentioning

confidence: 99%

Metal nanoparticles-based nanoplatforms for colorimetric sensing: A review

Jin

Wang

2020

Reviews in Analytical Chemistry

View full text Add to dashboard Cite

With the progress of analysis technology and nanotechnology, colorimetric detection has become one of the research hotspots in the field of analytical chemistry. Compared with traditional detection methods, the colorimetric method has many advantages, such as high sensitivity, good selectivity, convenience and fast, as well as low cost. In recent years, metal nanoparticles have been introduced into colorimetry, making the research and application of colorimetry develop rapidly. In this work, we summarize the usual colorimetric detection methods based on metal nanoparticles-based nanozymes and their applications in the last five years. We hope that this work will help readers understand the mechanism and practical application value of nanozyme-based colorimetric biosensors. Meanwhile, this work may give some hints and references for future colorimetric detection research to promote the application and development of nanozyme-based colorimetry in biomedical and environmental analysis.

show abstract

Prussian blue nanocubes peroxidase mimetic-based colorimetric assay for screening acetylcholinesterase activity and its inhibitor

Cited by 46 publications

References 55 publications

A gold nanoparticle based colorimetric and fluorescent dual-channel probe for acetylcholinesterase detection and inhibitor screening

A gold nanoparticle based colorimetric and fluorescent dual-channel probe for acetylcholinesterase detection and inhibitor screening

Nanozyme-Participated Biosensing of Pesticides and Cholinesterases: A Critical Review

Metal nanoparticles-based nanoplatforms for colorimetric sensing: A review

Contact Info

Product

Resources

About