Pruritus, Staphylococcus aureus, and human immunodeficiency virus infection

HIV seronegative eosinophilic pustular folliculitis successfully treated with doxicycline

“…infections, has been described. 14,15 Some authors suggest that an unidentified organism may act as a trigger rather than as a causative agent for the development of inflammatory reaction around follicle. This organism would be eliminated by the inflammatory responses, making its direct identification at clinical EPF onset virtually impossible.…”

“…Although EPF was initially defined as a sterile folliculitis of unknown cause, in several patients a causative factor, such as Pseudomonas spp., Staphyloccus aureus , Demodex folliculorum or Pityrosporum spp. infections, has been described 14,15 . Some authors suggest that an unidentified organism may act as a trigger rather than as a causative agent for the development of inflammatory reaction around follicle.…”

Photosensitivity in HIV‐Infected Individuals

“…Eosinophilia and an elevated IgE level are also seen with advanced HIV disease. Indeed, marked hypereosinophilia and massive IgE elevations (>10,000 U /mL) are seen in a small subset of photosensitive HIVinfected persons (16). In fact, numerous reports of "hyperosinophilic syndrome" in HIV disease document a "dermatitis" which may occur in the sun exposed areas (17)(18)(19)(20).…”

Skin Diseases Associated with HIV Infection

“…Although HIV-infected individuals are susceptible to multiple bacterial pathogens, Staphylococcus aureus is the most commonly encountered bacterial pathogen in HIV disease. Studies have documented the S. aureus nasal carriage rate in HIVinfected patients to be twice that of control groups [37].1t is known that in AIDS the migration and chemotactic response of neutrophils is markedly selective [38]. In fact delayed migration of neutrophils enhances the ability of the bacteria to produce disease [38].…”