Provitamin A Carotenoids

Perveen, Shagufta; Zafar, Sara; Iqbal, Naeem; Riaz, Muhammad

doi:10.1007/978-3-030-46459-2_26

Cited by 2 publications

(1 citation statement)

References 105 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The body converts provitamin A carotenoids into retinol. Among these carotenoids, β-carotene has full biological activity, while α-carotene and β-cryptoxanthin exhibit partial biological activity, compared to retinol [4]. Vitamin A in the form of retinoic acid carries out its functions primarily by interacting with nuclear receptors known as retinoic acid receptors (RAR) and retinoid X receptors (RXR) [5].…”

Section: Introductionmentioning

confidence: 99%

Plasma Retinol Concentrations and Dietary Intakes of Mother–Infant Sets in Singleton versus Twin Pregnancy

et al. 2023

View full text Add to dashboard Cite

Vitamin A (retinol) is essential for normal fetal development, but the recommendation for maternal dietary intake (Retinol Activity Equivalent, RAE) does not differ for singleton vs. twin pregnancy, despite the limited evaluation of retinol status. Therefore, this study aimed to evaluate plasma retinol concentrations and deficiency status in mother–infant sets from singleton vs. twin pregnancies as well as maternal RAE intake. A total of 21 mother–infant sets were included (14 singleton, 7 twin). The HPLC and LC-MS/HS evaluated the plasma retinol concentration, and data were analyzed using the Mann–Whitney U test. Plasma retinol was significantly lower in twin vs. singleton pregnancies in both maternal (192.2 vs. 312.1 vs. mcg/L, p = 0.002) and umbilical cord (UC) samples (102.5 vs. 154.4 vs. mcg/L, p = 0.002). The prevalence of serum-defined vitamin A deficiency (VAD) <200.6 mcg/L was higher in twins vs. singletons for both maternal (57% vs. 7%, p = 0.031) and UC samples (100% vs. 0%, p < 0.001), despite a similar RAE intake (2178 vs. 1862 mcg/day, p = 0.603). Twin pregnancies demonstrated a higher likelihood of vitamin A deficiency in mothers, with an odds ratio of 17.3 (95% CI: 1.4 to 216.6). This study suggests twin pregnancy may be associated with VAD deficiency. Further research is needed to determine optimal maternal dietary recommendations during twin gestation.

show abstract

Section: Introductionmentioning

confidence: 99%

Plasma Retinol Concentrations and Dietary Intakes of Mother–Infant Sets in Singleton versus Twin Pregnancy

et al. 2023

View full text Add to dashboard Cite

show abstract

The potential of provitamin A maize ( Zea mays L.) biofortification in sub-Saharan Africa: Current status, opportunities, challenges and perspectives: A review

Mudadirwa,

Ndhlela,

Olakojo

et al. 2023

CABI Reviews

View full text Add to dashboard Cite

Maize is a potential crop for improving food and nutritional security for over 300 million people in sub-Saharan Africa (SSA). It is the most preferred cereal crop in SSA because of its diversified uses, taste and higher grain yield potential compared to other cereals. However, overdependence on maize-based diets without vitamin A supplementation is associated with the highest rates of vitamin A deficiency (VAD) in SSA. Vitamin A deficiency mostly affects children under the age of 5 years, pregnant and lactating women, accounting for the worst disease burden, and infant mortality in SSA. To date provitamin A maize breeding programmes of HarvestPlus partnered with CIMMYT and IITA, private seed companies and national plant breeding programmes developed at least 70 elite varieties to curb VAD in SSA. This review summarizes the potential of provitamin A maize in SSA focusing on (1) reasons why maize is a good choice for provitamin A biofortification, (2) the prevalence of vitamin A deficiency in SSA, (3) the Global Hunger Index (GHI) and extent of hidden hunger, (4) possible interventions to curb vitamin A deficiency in SSA and their applicability, (5) status of the provitamin A maize varieties released, (6) level of adoption and consumer perception of provitamin A maize-based food, (7) the impact of climate change in maize productivity in SSA and (8) the breeding methods for developing provitamin A maize-resilient genotypes to mitigate the effects of climate change in SSA.

show abstract

Provitamin A Carotenoids

Cited by 2 publications

References 105 publications

Plasma Retinol Concentrations and Dietary Intakes of Mother–Infant Sets in Singleton versus Twin Pregnancy

Plasma Retinol Concentrations and Dietary Intakes of Mother–Infant Sets in Singleton versus Twin Pregnancy

The potential of provitamin A maize ( Zea mays L.) biofortification in sub-Saharan Africa: Current status, opportunities, challenges and perspectives: A review

Contact Info

Product

Resources

About