Protein Shape Retrieval

Surface-based protein domains retrieval methods from a SHREC2021 challenge

“…This track reveals significantly lower results when compared to past tracks [31][32][33][34]. However, satisfactory solutions exist to distinguish between loosely related proteins, or to identify identical proteins with different conformations, based on their shapes only.…”

“…Compared to previous SHREC datasets dealing with protein structures or surfaces [29][30][31][32][33][34], the SHREC ′ 21 protein track dataset is characterized by three main aspects: (1) the presence of two datasets representing the same set of proteins, one shape-only and one shape + electrostatic dataset, (2) the close evolutionary relationship of some of the query domains, further characterized by a similar topology (Fig. 1), (3) the intermediate similarity of the domains topologies (Fig.…”