volume 66, issue 6, P3950-3954 1992
DOI: 10.1128/jvi.66.6.3950-3954.1992
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Abstract: Rhesus macaques were immunized with live vaccinia virus recombinants expressing the envelope glycoproteins (gp7O and gp22) of simian type D retrovirus (SRV), serotype 1 or 3. All of the animals immunized with either the SRV-1 env or the SRV-3 env vaccinia virus recombinant developed neutralizing antibodies against the homologous SRV. In addition, both groups developed cross-reactive antibodies and were protected against an intravenous live-virus challenge with SRV-1. The four control animals immunized with a v…

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