Abstract:Adaptation to different environmental temperatures establishes specific requirements on the stability of DNA and protein macromolecules. Organismal strategies of thermophilic adaptation, structure‐ and sequence‐based, and their physical origins provide a consistent picture of the evolution of protein thermostability. A strong correlation between the optimal growth temperature (OGT) and the frequency of ApG dinucleotides in both sense and antisense strands of genomic DNA along with the absence of any “thermoph… Show more
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