Protective role of propolis against reproductive toxicity of triphenyltin in male rabbits

Yousef, Mokhtar I.; Kamel, Kamel I.; Hassan, Mervat S.; El-Morsy, A.M.

doi:10.1016/j.fct.2010.04.018

Cited by 58 publications

(57 citation statements)

References 42 publications

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“…The findings of the present work are in line with some studies which reported that propolis could protect against the toxicity of several chemical and environmental toxic substances [31][32][33] . This potential might be related to its pharmacological and biological contents such as flavonoid compounds and phenolic acids.…”

Section: Discussionsupporting

confidence: 81%

“…This might indicate potential capability of propolis to suppress glomerular filtration surface and interstitial renal capillary expansion related to its ability to prevent lipid peroxidation by activation of some antioxidant enzymes 14,17,29 . Several studies reported that propolis could protect the mitochondria and cellular macromolecules against oxidative damage [32][33][34] . In addition, the protective role of propolis against formation of hyaline casts might indicate an ability to ameliorate protein disturbances induced by GNPs (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, propolis has the ability to activate antioxidant enzymes to suppress cytochrome p-450 enzymes and to reduce lipid peroxidation 19,21,30 . In addition, some investigators reported that propolis can inhibit membrane free radical formation and has the capability to protect the mitochondria and cellular macromolecules against oxidative damage 31,32 . It might be concluded from the findings of the present work that propolis can augment the antioxidant defence against the severity of some alterations in renal tissues induced by GNPs (Fig.…”

Section: Discussionmentioning

confidence: 99%

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Protective role of propolis against histological alterations in renal tissue induced by gold nanoparticles

Al‐Μansour¹,

Alferah²,

Jarrar³

2016

ScienceAsia

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ABSTRACT:Male albino Wistar rats were exposed to 10 nm gold nanoparticles at a dose of 2000 µg/kg together with or without propolis (50 mg/kg) for 15 consecutive days. Fresh renal biopsies from of all investigated rats were cut rapidly, fixed in neutral buffered formalin, subjected to histological processing, and examined for microanatomical alterations. Propolis gave full protection against glomerular congestion and renal tubule hyaline casts. It demonstrated partial amelioration against glomerular capillary dilatation, tubular cloudy swelling, necrosis, and degeneration together with interstitial blood capillaries dilatation and haemorrhage induced by nanoparticle toxicity. On the other hand, propolis showed no protective effect against renal cells pyknosis, karyolysis, apoptosis and renal hydropic degeneration together with collecting tubules atrophy and degeneration induced by the nanoparticles. Thus propolis can augment the antioxidant defence against the severity of some alterations in the renal tissues. This ameliorative role might be related to the antioxidants content of propolis that protect the renal tissues from free radicals and oxidative stress.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Protective role of propolis against histological alterations in renal tissue induced by gold nanoparticles

Al‐Μansour¹,

Alferah²,

Jarrar³

2016

ScienceAsia

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“…This was also observed by Yousef et al (2010), in rabbits, by administering daily, 50 mg/kg of body weight of propolis orally, for 12 weeks. Perhaps, the antioxidant properties of flavonoids (VASCONCELLOS et al, 2007;SYAZANA et al, 2011) found in propolis, among other factors, have contributed to improve sperm morphology, acting as antioxidant elements, protecting the sperm membrane.…”

Section: Resultsmentioning

confidence: 85%

“…Propolis generally contains 40 to 70% of resins and balsams, 20 to 35% of wax, 3 to 5% of essential oils and 5% of pollen grains (BOGDANOV;BANKOVA, 2014). It has been demonstrated that propolis provides protection against infertility by improving sperm production, motility, count and quality, and increased the process of steroidogenesis and hence testosterone production (YOUSEF; SALAMA, 2009), and could help in productions variables like body weight and feed intake due to high content of flavonoids (YOUSEF et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Inclusion of Propolis in Rabbit Diets and Semen Characteristics

Moraes

Mataveli

Moura

et al. 2015

ArqVet

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Milene Puntel Osmari 1 MORAES, G. V. de; MATAVELI, M.; MOURA, L. P. P. de; SCAPINELLO, C.; MORA, F.; OSMARI, M. P. Inclusion of própolis in rabbits diets and sêmen characteristics. Arq. Ciênc. Vet. Zool. UNIPAR, Umuarama, v. 17, n. 4, p. 227-231, out./ dez. 2014. ABSTRACT:This experiment was carried out with the objective of evaluating different levels of powder propolis in rabbit diets and their effect on semen characteristics. A total of 36 New Zealand White male rabbits were used, randomly distributed into six groups, corresponding to six propolis levels (0, 0.25, 0.50, 0.75, 1.0 and 1.25 g propolis/kg of ration). Semen was collected twice a week, using an artificial vagina. Semen volume, progressive spermatic motility, spermatic vigor, spermatic concentration and spermatic morphology were analyzed. General linear models were used for statistical analysis. The inclusion of powder propolis in the diet increased normal spermatozoa percentage and reduced spermatozoa abnormalities. The powder propolis did not affect the progressive spermatic motility, spermatic vigor or spermatic concentration. The values were considered normal for rabbits. However, a small reduction in semen volume was observed, without any negative effect on the other semen characteristics evaluated. Thus, it is possible to observe better semen quality with the inclusion of 1.25 g powder propolis/kg in the diet for reproducer rabbits. KEYWORDS: Reproduction. Reproducer. Semen evaluation. INCLUSÃO DE PRÓPOLIS NA DIETA DE COELHOS E CARACTERÍSTICAS DO SÊMENRESUMO: Este experimento foi realizado com o objetivo de avaliar a influência de diferentes níveis de própolis em pó na ração de coelhos sobre as características do sêmen. Utilizaram-se 36 coelhos machos, adultos, Nova Zelândia Brancos, divididos aleatoriamente em seis grupos, consumindo cinco níveis de própolis (0; 0,25; 0,50; 0,75; 1,0 e 1,25 g de própolis/kg de ração). Coletou-se sêmen duas vezes por semana, utilizando vagina artificial. Verificou-se o volume, a motilidade espermática progressiva, o vigor espermático, a concentração espermática e a morfologia espermática. As análises estatísticas foram realizadas utilizando os modelos lineares generalizados. A adição da própolis na ração elevou a porcentagem de espermatozóides normais e reduziu os anormais. Todavia, foi observada uma pequena redução no volume do sêmen com o aumento do nível de própolis na dieta, sem afetar as demais características do sêmen. A motilidade progressiva, vigor espermático e concentração espermática não foram influenciados pelos diferentes níveis de própolis, valores considerados normais para coelhos. Conclui-se que a melhor qualidade do sêmen de coelhos reprodutores ocorreu com a adição de 1,25 g de própolis/kg de ração. PALAVRAS-CHAVE: Avaliação de sêmen. Reprodução. Reprodutores. INCLUSIÓN DE PROPÓLEOS EN LA DIETA DE CONEJOS Y CARACTERÍSTICAS DEL SEMEN RESUMEN:Este experimento se llevó a cabo para evaluar la influencia de diferentes niveles de polvo de propóleos en la dieta de conejos, bajo las características...

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Novel Immunological Aspects for the Treatment of Age‐induced Ovarian and Testicular Infertility, Other Functional Diseases, and Early and Advanced Cancer Immunotherapy

Bukovský

2016

Human Reproduction

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Protective role of propolis against reproductive toxicity of triphenyltin in male rabbits

Cited by 58 publications

References 42 publications

Protective role of propolis against histological alterations in renal tissue induced by gold nanoparticles

Protective role of propolis against histological alterations in renal tissue induced by gold nanoparticles

Inclusion of Propolis in Rabbit Diets and Semen Characteristics

Novel Immunological Aspects for the Treatment of Age‐induced Ovarian and Testicular Infertility, Other Functional Diseases, and Early and Advanced Cancer Immunotherapy

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