Protective role of gallic acid against fenitrothion-induced hepatotoxicity and nephrotoxicity via oxidative stress, histopathological and biochemical alterations
Abstract:Fenitrothion (FNT) is a known environmental contaminant used in public health and agriculture. Gallic acid (GA) is a phenolic compound found in numerous plants. This study analyzed the hepatotoxic and nephrotoxic effects of FNT and to evaluate the possible protective effect of gallic acid. FNT (1/25 LD50, 32 mg/kg body weight/day), and gallic acid (50 mg/kg body weight/day) were administrated to male rats by gavage for 28 days. In the present study, the renal (blood urea nitrogen, creatinine and uric acid leve… Show more
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