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Cited by 59 publications
(30 citation statements)
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“…Alteration of tight junction structure was also observed in cells exposed to toxic bile acids [30,31]. On the other hand, cholestasis is correlated with systemic oxidative stress [32,33], which is thought to play a key role in the associated cellular injury [34,35].…”
Section: Discussionmentioning
confidence: 99%
“…Alteration of tight junction structure was also observed in cells exposed to toxic bile acids [30,31]. On the other hand, cholestasis is correlated with systemic oxidative stress [32,33], which is thought to play a key role in the associated cellular injury [34,35].…”
Section: Discussionmentioning
confidence: 99%
“…Chromium induced-hepatotoxicity may be attenuated by several compounds [8385]. The antihepatotoxic effects of curcumin against liver injury are well recognized and attributed to its intrinsic antioxidant properties [8688]. …”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, curcumin is the main active compound of Curcuma longa L. and is considered a bifunctional antioxidant, its consumption, in both animals and humans, has been recognized as safe by the Food and Drug Administration . Curcumin is an effective ROS scavenger; it is able to scavenge superoxide anion ( O2), singlet oxygen, hydrogen peroxide (H 2 O 2 ), peroxynitrite anion, hypochlorous acid, hydroxyl radicals, and peroxyl radicals .…”
Section: Introductionmentioning
confidence: 99%