Protective effects of 2,3,5,4′-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice

Plant-Derived Agents with Anti-Glycation Activity

“…is a natural compound with strong antioxidative and anti-inflammatory properties, which has been reported as the major bioactive compound from Polygonum multiflorum Thunb., a traditional Chinese herbal tea [151,152]. It was shown to efficiently inhibit the formation of AGEs in a dose-dependent manner by trapping reactive MGO under physiological conditions (pH 7.4, 37°C) [153].…”

2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside protects murine hearts against ischemia/reperfusion injury by activating Notch1/Hes1 signaling and attenuating endoplasmic reticulum stress

“…C57Bl/6 mice were orally gavaged with TSG at a dose of 60 mg/kg body weight per day for 2 weeks. The TSG dose was selected based on previous studies [16,27,28] . Two weeks after the treatment, MI/R surgery was performed as previously described [29] .…”

Novel agents for enzymatic and fungal hydrolysis of stevioside

“…Cardenolides are good examples of bioactive glycosides, possessing high cardiotonic (22) and cytotoxic (5) activities. Other interesting biologically active examples include cucurbitacin glycosides, possessing free-radical scavenging properties (29), antocianins, that promote a protective effect against H 2 O 2 -or TNF-induced insulin resistance in 3T3-L1 adipocytes (12) and stilbene glycosides, active anti-inflammatory compounds (31).…”