2020
DOI: 10.4067/s0717-95022020000200340
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: AL-DOAISS, A. A. & AL-SHEHRI, M. A.Protective effect of gum Arabic/insulin against histological changes in testes of diabetic rats.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
5
0

Year Published

2021
2021
2022
2022

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 7 publications
(5 citation statements)
references
References 16 publications
0
5
0
Order By: Relevance
“…The role of AG in the improvement of radiation-induced kidney and liver dysfunction might be attributed to its antioxidant, anti-inflammatory and cytoprotective properties [45] in addition to downregulation of the levels of hepatic caspase-3, interleukin -β1, interleukin -6 and tumor necrosis factor -α (TNF-α) genes [46] and immunomodulatory effects [47],through scavenging superoxide anions [48] and inhibiting lipid peroxidation [49] AG protects the cell membrane from radiation-induced oxidative damage. This is supported by the fact that AG has high affinity to free radicals [39]. Published reports showed the numerous biological activities of Acacia species such as hypoglycemic, antitumor, anti-inflammatory [11], anti-hepatitis C virus, spasmogenic and vasoconstrictor, antiplatelet aggregation, antihypertensive [49], and antioxidant potential [50], together with wound healing [51].…”
Section: Discussionmentioning
confidence: 94%
See 1 more Smart Citation
“…The role of AG in the improvement of radiation-induced kidney and liver dysfunction might be attributed to its antioxidant, anti-inflammatory and cytoprotective properties [45] in addition to downregulation of the levels of hepatic caspase-3, interleukin -β1, interleukin -6 and tumor necrosis factor -α (TNF-α) genes [46] and immunomodulatory effects [47],through scavenging superoxide anions [48] and inhibiting lipid peroxidation [49] AG protects the cell membrane from radiation-induced oxidative damage. This is supported by the fact that AG has high affinity to free radicals [39]. Published reports showed the numerous biological activities of Acacia species such as hypoglycemic, antitumor, anti-inflammatory [11], anti-hepatitis C virus, spasmogenic and vasoconstrictor, antiplatelet aggregation, antihypertensive [49], and antioxidant potential [50], together with wound healing [51].…”
Section: Discussionmentioning
confidence: 94%
“…Antioxidants appear to improve the condition of the blood vessels by helping to neutralize free radical molecules or ROS that may inhibit blood vessel-lining endothelial cells from liberating nitric oxide, which is responsible for blood vessel dilatation [38]. Al-Doaiss and Al-Shehri [39] interpreted the antioxidant effects of AG by its ability to trigger endogenous glutathione levels and to suppress lipid peroxidation in rats' blood, liver and kidney tissues. Pal et al [40] indicated that the hydro-alcoholic extract of Acacia senegal had significant hepatoprotective activity, probably due to its high flavonoid content.…”
Section: Discussionmentioning
confidence: 99%
“…Treating experimental animals with GA has successfully ameliorated the histology alterations observed on the testicular tissue of rats. Experimental data revealed that GA remarkably improved the injurious changes of testes [47]. Another study showed that consumption of GA resulted in decreased lipid peroxidation, amelioration in degenerative testicular tissue of alloxan-induced diabetic rats, and enhanced sperm quality, activity of the endogenous antioxidant enzymes together with their expressed proteins were collectively found to be increased.…”
Section: Role Of Ga In Diabetic Testicular Degeneration and Erectile Dysfunctionmentioning
confidence: 95%
“…Gum Arabic is a natural binder from the hardened sap of acacia trees. Gum Arabic is found in the Middle East and North Africa [23,24]. It is called Gum Arabic because it is exported from Arabia countries [24].…”
Section: Introductionmentioning
confidence: 99%
“…Its chemical properties and features are being used in a wide range of industrial sectors such as textiles, ceramics, lithography, cosmetics and pharmaceuticals, encapsulation, food, etc [24]. For example, it is used worldwide as a stabilizer in wine, soft drink, candies, cosmetics, postage stamps, envelopes, paint and traditional treatment of diverse diseases [23]. Gum Arabic has great potential in the construction industry.…”
Section: Introductionmentioning
confidence: 99%