Cell Reports volume 3, issue 3, P587-594 2013 DOI: 10.1016/j.celrep.2013.02.006 View full text
Elodie Lanet, Alex P. Gould, Cédric Maurange

Abstract: SummarySystemic signals provided by nutrients and hormones are known to coordinate the growth and proliferation of different organs during development. However, within the brain, it is unclear how these signals influence neural progenitor divisions and neuronal diversity. Here, in the Drosophila visual system, we identify two developmental phases with different sensitivities to dietary nutrients. During early larval stages, nutrients regulate the size of the neural progenitor pool via insulin/PI3K/TOR-dependen…

expand abstract