Antonino Schepis, Adrian Barker, Yoga Srinivasan, Eaman Balouch, Yaowu Zheng, Ian Lam, Hilary Clay, Chung-Der Hsiao, Shaun R. Coughlin
Abstract:Mechanisms that sense and regulate epithelial morphogenesis and homeostasis are incompletely understood. Schepis et al. provide evidence that protease-activated receptor Par2b and matriptase, a membrane-tethered protease, can regulate apical extrusion and other epithelial responses involved in tissue remodeling and inflammation.
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