Prostate cancer presentation, treatment selection, and outcomes among men with HIV/AIDS: A clinical stage, race, and age-matched contemporary analysis

Prostate Cancer Outcomes in Patients Living With HIV/AIDS Treated With Radiation Therapy: A Systematic Review

“…As reported in 7 studies, the average duration between HIV infection and PCa diagnosis ranged from 8.5-18.6 years (13,14,15,16,18,20,21). The majority of patients were on HAART at the time of PCa diagnosis (range, 69-100%) and the average CD4 count ranged from 336-523 cells/mm³.…”

“…Table 1 and 2 summarize the patient demographics and the characteristics of HIV infection, respectively. A total of 187 HIV-positive patients were included in 9 studies (13)(14)(15)(16)(17)(18)(19)(20)(21). Three articles, which notably have been published in the last 10 years, included a control arm with a total of 1 659 HIV-negative patients (13,15,17).…”

“…A total of 187 HIV-positive patients were included in 9 studies (13)(14)(15)(16)(17)(18)(19)(20)(21). Three articles, which notably have been published in the last 10 years, included a control arm with a total of 1 659 HIV-negative patients (13,15,17). A matched cohort analysis for patient age, race, and tumor stage was performed in 2 of these 3 studies (13,17).…”

“…Patient race was reported for 149 patients in 6 of the 9 studies: 118 (79%) African American, 21 (14%) White, 8 (5%) Hispanic, and 2 unknown (1.3%) (13,15,16,17,20,21). Of the 3 studies with a control group, Kahn et al and Ruden et al had matched controls (13,17).…”

“…Patient race was reported for 149 patients in 6 of the 9 studies: 118 (79%) African American, 21 (14%) White, 8 (5%) Hispanic, and 2 unknown (1.3%) (13,15,16,17,20,21). Of the 3 studies with a control group, Kahn et al and Ruden et al had matched controls (13,17). Meanwhile, Reidel et al included 1 496 PCa patients from the general population, which had a greater frequency of White patients (52%) and lower frequency of African Americans (45%) compared to HIV-positive patients (15).…”