Prospects of pulsed amperometric detection in flow-based analytical systems - A review

Islam, Muhammed Ariful; Mahbub, Parvez; Nesterenko, Pavel N.; Paull, Brett; Macka, Mirek

doi:10.1016/j.aca.2018.10.066

Cited by 38 publications

(22 citation statements)

References 179 publications

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“…Electrochemical detection is an extremely selective and sensitive detection technique [116, 117]. Amperometric detection (AD) is the most commonly employed electrochemical detection technique.…”

Section: O‐phthaldialdehydementioning

confidence: 99%

Homocyclic o‐dicarboxaldehydes: Derivatization reagents for sensitive analysis of amino acids and related compounds by capillary and microchip electrophoresis

Celá

Glatz

2020

Electrophoresis

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Amino acids are essential compounds for living organisms, and their determination in biological fluids is crucial for the clinical analysis and diagnosis of many diseases. However, the detection of most amino acids is hindered by the lack of a strong chromophore/fluorophore or electrochemically active group in their chemical structures. The highly sensitive determination of amino acids often requires derivatization. Capillary electrophoresis is a separation technique with excellent characteristics for the analysis of amino acids in biological fluids. Moreover, it offers the possibility of precapillary, on‐capillary, or postcapillary derivatization. Each derivatization approach has specific demands in terms of the chemistry involved in the derivatization, which is discussed in this review. The family of homocyclic o‐dicarboxaldehyde compounds, namely o‐phthalaldehyde, naphthalene‐2,3‐dicarboxaldehyde, and anthracene‐2,3‐dicarboxaldehyde, are powerful derivatization reagents for the determination of amino acids and related compounds. In the presence of suitable nucleophiles they react with the primary amino group to form both fluorescent and electroactive derivatives. Moreover, the reaction rate enables all of the derivatization approaches mentioned above. This review focuses on articles that deal with using these reagents for the derivatization of amino acids and related compounds for ultraviolet‐visible spectrometry, fluorescence, or electrochemical detection. Applications in capillary and microchip electrophoresis are summarized and discussed.

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Section: O‐phthaldialdehydementioning

confidence: 99%

Homocyclic o‐dicarboxaldehydes: Derivatization reagents for sensitive analysis of amino acids and related compounds by capillary and microchip electrophoresis

Celá

Glatz

2020

Electrophoresis

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“…High‐throughput screening methods using enzymes have garnered continuous interest in pharmaceutical sciences [1–14], biochemistry [5], and biocatalysis [6,7]. Enzyme‐linked immunosorbent assay (ELISA) [8–10] and flow cytometry [11–13] are well‐known technologies for high‐throughput screening owing to their high sensitivity and throughput capacity; further, these methods require the use of fluorescence molecules.…”

Section: Introductionmentioning

confidence: 99%

“…Traditional electrochemical approaches are capable of obtaining fast response times, have electrode arrays and simple instrumentation and operation, and enable electronic measurements without specially designed fluorescence molecules. Therefore, they are effective for high‐throughput screening because of these advantages [14,15].…”

Section: Introductionmentioning

confidence: 99%

Light‐Addressable Amperometric Sensor with Counter and Working Electrodes of the Same Material

Kosugi

Hasegawa

Uchida

2021

IEEJ Transactions Elec Engng

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High‐throughput screening is important in various fields, and electrochemical approaches are effective because of advantages such as fast response time and electrode array. Hence, we developed a two‐dimensional electrochemical array sensor. However, its signal intensities for lower concentrations of the redox pair (100 μM–100 pM [Fe[CN]6]3−/4−) were unstable; Therefore, in this study, we investigated and demonstrated a method for improving the signal stability at lower concentrations. Two types of counter electrodes were prepared to assess their influence; the material of the first electrode was the same as that of the working electrode (same material condition), and the other was prepared from a different material (different material condition). First, the differences in the electric potentials between different materials were investigated at lower concentrations. Furthermore, the concentration dependence was investigated using our newly developed light‐addressable amperometric sensor for the two conditions. In the different condition, it was observed that differences in the electric potentials between the electrodes at lower concentrations. It was also observed that the signal intensity was more stable for the same material condition than the different material condition. Limit of detection(LOD) for the same material condition was lower than that under the different material condition. The proposed method using the same materials is thus an effective means to measure low concentrations of redox ions and expected to contribute to a fabrication of a smaller and more stable device without reference electrode. © 2021 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC.

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“…in 2001 and Santos et al . in 2008, this combined technique (FIA‐MPA) has been employed for the simultaneous determination of two or more target analytes in different matrixes – see the review by Islam et al . The FIA‐MPA technique consists in, firstly, inserting an aliquot of the sample into the FIA system, which is transported by the carrier solution towards the detector.…”

Section: Introductionmentioning

confidence: 99%

Simple Flow Injection Analysis System Coupled to Multiple‐Pulse Amperometry and a Boron‐Doped Diamond Electrode for the Simultaneous Determination of Sunset Yellow and Aspartame

et al. 2020

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The first electroanalytical method for the simultaneous determination of the colorant sunset yellow (SY) and the sweetener aspartame (AS) in commercial food samples is proposed using flow injection analysis coupled to multiple-pulse amperometry (FIA-MPA) and an anodically pretreated boron-doped diamond electrode (APT-BDDE). Dual-potential waveforms are applied as a function of time: E det.1 = 1.30 V/150 s for the oxidation only of SY, and E det.2 = 1.70 V/200 s for the oxidation of both analytes. Linear analytical curves were obtained in the concentration range of 0.15-25.0 μmol L À 1 for SY and 0.25-25.0 μmol L À 1 for AS, with a calculated limit of detection of 0.04 μmol L À 1 for both analytes. The proposed method presented good precision and enabled the simultaneous determination of SY and AS in samples of jelly and juice powders with a good accuracy (at a 95 % confidential level) when compared to an HPLC method. The proposed FIA-MPA method is simple and fast, with an analytical frequency of 120 determinations per hour, being an attractive option for routine simultaneous determinations of SY and AS.[a] Dr.

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Prospects of pulsed amperometric detection in flow-based analytical systems - A review

Cited by 38 publications

References 179 publications

Homocyclic o‐dicarboxaldehydes: Derivatization reagents for sensitive analysis of amino acids and related compounds by capillary and microchip electrophoresis

Homocyclic o‐dicarboxaldehydes: Derivatization reagents for sensitive analysis of amino acids and related compounds by capillary and microchip electrophoresis

Light‐Addressable Amperometric Sensor with Counter and Working Electrodes of the Same Material

Simple Flow Injection Analysis System Coupled to Multiple‐Pulse Amperometry and a Boron‐Doped Diamond Electrode for the Simultaneous Determination of Sunset Yellow and Aspartame

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