2019
DOI: 10.1002/bjs.11025
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Abstract: Background The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high‐ (HICs) and low‐ and middle‐income countries (LMICs). Methods This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospectiv… Show more

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Cited by 12 publications
(3 citation statements)
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“…Blood sampling is performed daily for the first 3 days after surgery, with the specific troponin assays being the preferred assays at each study site. Research personnel also document specific complications (table 2), with the most severe complication being further characterised using a modified International Surgical Outcomes Study scheme 38. In this classification scheme, the most severe complication is classified as mild (resulted in only temporary harm and did not require clinical treatment), moderate (required clinical treatment but without causing significant prolongation of hospital stay or permanent functional limitation), severe (required clinical treatment and resulted in significant prolongation of hospital stay and/or permanent functional limitation) or fatal (resulted in death).…”
Section: Methods and Analysismentioning
confidence: 99%
“…Blood sampling is performed daily for the first 3 days after surgery, with the specific troponin assays being the preferred assays at each study site. Research personnel also document specific complications (table 2), with the most severe complication being further characterised using a modified International Surgical Outcomes Study scheme 38. In this classification scheme, the most severe complication is classified as mild (resulted in only temporary harm and did not require clinical treatment), moderate (required clinical treatment but without causing significant prolongation of hospital stay or permanent functional limitation), severe (required clinical treatment and resulted in significant prolongation of hospital stay and/or permanent functional limitation) or fatal (resulted in death).…”
Section: Methods and Analysismentioning
confidence: 99%
“…Annually, more than 310 million surgical interventions are performed and most require general anesthesia with neuromuscular blockade and positive pressure ventilation [75,76]. Many operations last longer than 2-3 h and are accompanied by increased risk of respiratory complications (Fig.…”
Section: Protective Ventilation During Perioperative Periodmentioning
confidence: 99%
“…To date, most research on high-risk patients has focused on risk of death and complications in the immediate postoperative period. 7 , 8 However, the long-term outcomes for high-risk patient groups remain poorly described, but important to understand for patients considering surgical treatments, and those planning their care. Around one in 15 patients require non-elective hospital admission in the year after surgery.…”
mentioning
confidence: 99%