Prospective Evaluation of Morphology, Function, and Quality of Life After Extracorporeal Shockwave Lithotripsy and Endoscopic Treatment of Chronic Calcific Pancreatitis

Brand, Boris; Kahl, Matthias; Sidhu, Sandeep Singh; Nam, V C; Sriram, Parupudi V.J.; Jaeckle, Stefan; Thonke, Frank; Soehendra, Nib

doi:10.1111/j.1572-0241.2000.03190.x

Cited by 135 publications

(77 citation statements)

References 30 publications

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“…In our study involving Italian patients with chronic pancreatitis [20], neither the type of pancreatic surgery nor endoscopic therapy were able to substantially modify the various physical and mental domains investigated by the SF-36 and this is in contrast to previous studies regarding the various surgical and endoscopic options [4,16,[22][23][24][25][26][27][28][29]; the difference may be due to the fact that these latter studies [4,16,[22][23][24][25][26][27][28][29] enrolled a highly selected group of patients with a short time interval between the intervention and the assessment of the health-related quality of life or that the data were not adjusted for sex and age.…”

Section: Chronic Pancreatitiscontrasting

confidence: 99%

Pancreatic Diseases: The Need to Assess the Quality of Life Raffaele Pezzilli

Pezzilli¹

2012

Pancreat Disorders Ther

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The patient's overall well-being and ability to function is one of the measures capable of quantifying the impact of disease and treatment. Health-related quality of life, as subjectively perceived by the patient, is becoming a major issue in the evaluation of any therapeutic intervention, mainly in patients with chronic diseases. In this paper, the literature regarding the well-being of patients with pancreatic diseases, both acute and chronic, and of patients who undergo surgery for their benign or malignant pancreatic disease will be reviewed. The conclusions that can be drawn from the studies reviewed are that the quality of life should be routinely assessed for evaluating patients with pancreatic diseases.

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Section: Chronic Pancreatitiscontrasting

confidence: 99%

Pancreatic Diseases: The Need to Assess the Quality of Life Raffaele Pezzilli

Pezzilli¹

2012

Pancreat Disorders Ther

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“…According to some studies [36,65,67], endoscopic therapy was not able to modify the various physical and mental domains evaluated by both the SF-36 [36,65] and SF-12 [67] questionnaire, whereas endoscopic therapy combined with ESWL was able to significantly improve some QoL scores (pain, weight loss, fever and jaundice) and the global QoL in about 70% of patients during a short time interval (median 7 mo, range: 5−9). Endoscopic therapy can affect the long-term clinical outcome by decreasing both the hospitalization rate for pain and the intake of analgesics [172,173]. Because of the frequent coexistence of different ductal lesions in the same patient, the effectiveness of endoscopic therapy is usually the result of combined procedures, such as sphincterotomy, stricture(s) dilation, stone(s) extraction, stent(s) placement.…”

Section: E2mentioning

confidence: 99%

“…ESWL overcomes the problem of the stone size by fragmenting the stones, thus facilitating endoscopic clearance of the duct. ESWL is required in 36−68% of patients and successful rates of stone clearance of the main pancreatic duct ranged from 37% to 100% [115,120,173,[179][180][181][182][183][184][185][186][187]. Use of ultrasound instead of x-rays to locate pancreatic stones is associated with a lower fragmentation rate [188,189].…”

Section: E3: Is Endoscopic Therapy Indicated In Chronic Pancreatitismentioning

confidence: 99%

Italian consensus guidelines for chronic pancreatitis

Frulloni

Falconi

Gabbrielli

et al. 2010

Digestive and Liver Disease

165

112

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This paper gives practical guidelines for diagnosis and treatment of chronic pancreatitis. Statements have been elaborated by working teams of experts, by searching for and analysing the literature, and submitted to a consensus process by using a Delphi modified procedure. The statements report recommendations on clinical and nutritional approach, assessment of pancreatic function, treatment of exocrine pancreatic failure and of secondary diabetes, treatment of pain and prevention of painful relapses. Moreover, the role of endoscopy in approaching pancreatic pain, pancreatic stones, duct narrowing and dilation, and complications was considered. Recommendations for most appropriate use of various imaging techniques and of ultrasound endoscopy are reported. Finally, a group of recommendations are addressed to the surgical treatment, with definition of right indications, timing, most appropriate procedures and techniques in different clinical conditions and targets, and clinical and functional outcomes following surgery. © 2010 Editrice Gastroenterologica Italiana S.r.l

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“…In Europe, ESWL is employed either primarily or secondarily after failure of endoscopic pancreatolithotripsy. 17,18 Recently, Delhaye 19 reported that ESWL can be used as a first-line treatment when obstructive ductal stones cause Chronic pancreatitis: new developments dilation of the main pancreatic duct (MPD) upstream. In Japan, ESWL is predominant with endoscopic treatment used adjunctively; 12,13,20,21 fragments of pancreatic stones pulverized by ESWL are collected using basket catheters.…”

Section: Treatment Of Chronic Pancreatitismentioning

confidence: 99%

New developments in diagnosis and non‐surgical treatment of chronic pancreatitis

Inui

Yoshino

Miyoshi

et al. 2013

J of Gastro and Hepatol

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Chronic pancreatitis is progressive and irreversible, leading to digestive and absorptive disorders by destruction of the exocrine pancreas and to diabetes mellitus by destruction of the endocrine pancreas. When complications such as pancreatolithiasis and pseudocyst occur, elevated pancreatic ductal pressure exacerbates pain and induces other complications, worsening the patient's general condition. Combined treatment with extracorporeal shock-wave lithotripsy and endoscopic lithotripsy is a useful, minimally invasive, firstline treatment approach that can preserve pancreatic exocrine function. Pancreatic duct stenosis elevates intraductal pressure and favor both pancreatolithiasis and pseudocyst formation, making effective treatment vitally important. Endoscopic treatment of benign pancreatic duct stenosis stenting frequently decreases pain in chronic pancreatitis. Importantly, stenosis of the main pancreatic duct increases risk of stone recurrence after treatment of pancreatolithiasis. Recently, good results were reported in treating pancreatic duct stricture with a fully covered self-expandable metallic stent, which shows promise for preventing stone recurrence after lithotripsy in patients with pancreatic stricture. Chronic pancreatitis has many complications including pancreatic carcinoma, pancreatic atrophy, and loss of exocrine and endocrine function, as well as frequent recurrence of stones after treatment of pancreatolithiasis. As early treatment of chronic pancreatitis is essential, the new concept of early chronic pancreatitis, including characteristics findings in endoscopic ultrasonograms, is presented.

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Prospective Evaluation of Morphology, Function, and Quality of Life After Extracorporeal Shockwave Lithotripsy and Endoscopic Treatment of Chronic Calcific Pancreatitis

Abstract: Besides pain relief, ESWL in combination with interventional endoscopy resulted in pancreatic ductal decompression, weight gain, and improvement in quality of life in a considerable number of patients with advanced CCP.

Cited by 135 publications

References 30 publications

Pancreatic Diseases: The Need to Assess the Quality of Life Raffaele Pezzilli

Pancreatic Diseases: The Need to Assess the Quality of Life Raffaele Pezzilli

Italian consensus guidelines for chronic pancreatitis

New developments in diagnosis and non‐surgical treatment of chronic pancreatitis

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