Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients

Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring

“…Before the occurrence of these grouped cases, the local recommendations for PCP prophylaxis in SOT recipients had been reduced compared with international recommendations. This reduced treatment protocol is in accordance with meta-analyses indicating that the risk/benefit ratio is only favorable when the incidence of PCP in the target population exceeds 3% 38 39 …”

Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring

“…Before the occurrence of these grouped cases, the local recommendations for PCP prophylaxis in SOT recipients had been reduced compared with international recommendations. This reduced treatment protocol is in accordance with meta-analyses indicating that the risk/benefit ratio is only favorable when the incidence of PCP in the target population exceeds 3% 38 39 …”

A Survey of Rheumatologists’ Practice for Prescribing Pneumocystis Prophylaxis

“…However, 4.3% of these patients who did not receive a prophylactic regimen and 17% of those on a prophylactic regimen of aerosolized pentamidine developed PCP 13,39 . Other studies have shown similar results 5,10,12,23 .…”

Outcomes of Pneumocystis jiroveci pneumonia infections in pediatric heart transplant recipients

“…None of the patients included in the study by Janner et al (12) received PJP prophylaxis. TMP/SMX has previously been shown to be a highly effective prophylactic medication for the prevention of PJP, with no infections found in eight studies in 407 patients taking prophylaxis (10). In our study, 16 of the 18 patients who did develop PJP were not on prophylaxis at the time of the acute infection, implying that prophylaxis is not 100% effective.…”

Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring

“…Before the occurrence of these grouped cases, the local recommendations for PCP prophylaxis in SOT recipients had been reduced compared with international recommendations. This reduced treatment protocol is in accordance with meta-analyses indicating that the risk/benefit ratio is only favorable when the incidence of PCP in the target population exceeds 3% 38 39 …”

A Survey of Rheumatologists’ Practice for Prescribing Pneumocystis Prophylaxis

“…However, 4.3% of these patients who did not receive a prophylactic regimen and 17% of those on a prophylactic regimen of aerosolized pentamidine developed PCP 13,39 . Other studies have shown similar results 5,10,12,23 .…”

Outcomes of Pneumocystis jiroveci pneumonia infections in pediatric heart transplant recipients

“…None of the patients included in the study by Janner et al (12) received PJP prophylaxis. TMP/SMX has previously been shown to be a highly effective prophylactic medication for the prevention of PJP, with no infections found in eight studies in 407 patients taking prophylaxis (10). In our study, 16 of the 18 patients who did develop PJP were not on prophylaxis at the time of the acute infection, implying that prophylaxis is not 100% effective.…”

Grouped Cases of Pulmonary Pneumocystosis After Solid Organ Transplantation: Advantages of Coordination by an Infectious Diseases Unit for Overall Management and Epidemiological Monitoring

“…Before the occurrence of these grouped cases, the local recommendations for PCP prophylaxis in SOT recipients had been reduced compared with international recommendations. This reduced treatment protocol is in accordance with meta-analyses indicating that the risk/benefit ratio is only favorable when the incidence of PCP in the target population exceeds 3% 38 39 …”

A Survey of Rheumatologists’ Practice for Prescribing Pneumocystis Prophylaxis

“…However, 4.3% of these patients who did not receive a prophylactic regimen and 17% of those on a prophylactic regimen of aerosolized pentamidine developed PCP 13,39 . Other studies have shown similar results 5,10,12,23 .…”

Outcomes of Pneumocystis jiroveci pneumonia infections in pediatric heart transplant recipients

“…None of the patients included in the study by Janner et al (12) received PJP prophylaxis. TMP/SMX has previously been shown to be a highly effective prophylactic medication for the prevention of PJP, with no infections found in eight studies in 407 patients taking prophylaxis (10). In our study, 16 of the 18 patients who did develop PJP were not on prophylaxis at the time of the acute infection, implying that prophylaxis is not 100% effective.…”