Prophylactic Photocoagulation of Recurrent Toxoplasmic Retinochoroiditis

Risk factors for recurrences and visual impairment in patients with ocular toxoplasmosis: A systematic review and meta-analysis

“…Also, another scheme with TMP/SMX was described by Fernandes Felix et al where they gave one dose of TMP160 mg/SMZ 800 every other day for 311 days, showing a single recurrence in 6 years in the experimental group [ 9 ]. Moreover, two studies report the use of photocoagulation for the prevention of reactivation; however, these studies do not have much methodological soundness and contradict each other [ 60 , 81 ]. Additionally, in immunosuppressed patients, the prophylactic scheme with P+Sdz seems to reduce the rate of recurrences, however, more studies are needed [ 84 ].…”

Risk factors for recurrences and visual impairment in patients with ocular toxoplasmosis: A systematic review and meta-analysis

“…Also, another scheme with TMP/SMX was described by Fernandes Felix et al where they gave one dose of TMP160 mg/SMZ 800 every other day for 311 days, showing a single recurrence in 6 years in the experimental group [ 9 ]. Moreover, two studies report the use of photocoagulation for the prevention of reactivation; however, these studies do not have much methodological soundness and contradict each other [ 60 , 81 ]. Additionally, in immunosuppressed patients, the prophylactic scheme with P+Sdz seems to reduce the rate of recurrences, however, more studies are needed [ 84 ].…”

Current Treatment of Toxoplasma Retinochoroiditis: An Evidence-Based Review

“…The first such approach historically was the application of laser photocoagulation directly on the lesion or in the immediately surrounding retina. For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37].…”

“…For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37]. However, in a case series of 35 patients that received laser photocoagulation around foci of Toxoplasma retinochoroiditis the recurrence rate was 53% in 5 years [38].…”

Laser Photocoagulation around the Foci of Toxoplasma Retinochoroiditis: A Descriptive Statistical Analysis of 35 Patients with Long-Term Follow-Up

“…As cysts are located in the neuroretina [4], they may be destroyed by the coagula tion process during the formation of the thermal damage. Rodriguez [19] in 1965 and Spatter et al [10] in 1966 first employed xenon lamp or argon laser photocoagulation in both active and inactive retinochoroiditis to shorten the in flammation period or to prevent recurrence. More recently, in 1989, Theodossiadis et al [12] studied the efficiency of argon laser photocoagulation in conjunction with medical treatment for active retinochoroiditis.…”

Risk factors for recurrences and visual impairment in patients with ocular toxoplasmosis: A systematic review and meta-analysis

“…Also, another scheme with TMP/SMX was described by Fernandes Felix et al where they gave one dose of TMP160 mg/SMZ 800 every other day for 311 days, showing a single recurrence in 6 years in the experimental group [ 9 ]. Moreover, two studies report the use of photocoagulation for the prevention of reactivation; however, these studies do not have much methodological soundness and contradict each other [ 60 , 81 ]. Additionally, in immunosuppressed patients, the prophylactic scheme with P+Sdz seems to reduce the rate of recurrences, however, more studies are needed [ 84 ].…”

Current Treatment of Toxoplasma Retinochoroiditis: An Evidence-Based Review

“…The first such approach historically was the application of laser photocoagulation directly on the lesion or in the immediately surrounding retina. For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37].…”

“…For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37]. However, in a case series of 35 patients that received laser photocoagulation around foci of Toxoplasma retinochoroiditis the recurrence rate was 53% in 5 years [38].…”

Laser Photocoagulation around the Foci of Toxoplasma Retinochoroiditis: A Descriptive Statistical Analysis of 35 Patients with Long-Term Follow-Up

“…As cysts are located in the neuroretina [4], they may be destroyed by the coagula tion process during the formation of the thermal damage. Rodriguez [19] in 1965 and Spatter et al [10] in 1966 first employed xenon lamp or argon laser photocoagulation in both active and inactive retinochoroiditis to shorten the in flammation period or to prevent recurrence. More recently, in 1989, Theodossiadis et al [12] studied the efficiency of argon laser photocoagulation in conjunction with medical treatment for active retinochoroiditis.…”

Risk factors for recurrences and visual impairment in patients with ocular toxoplasmosis: A systematic review and meta-analysis

“…Also, another scheme with TMP/SMX was described by Fernandes Felix et al where they gave one dose of TMP160 mg/SMZ 800 every other day for 311 days, showing a single recurrence in 6 years in the experimental group [ 9 ]. Moreover, two studies report the use of photocoagulation for the prevention of reactivation; however, these studies do not have much methodological soundness and contradict each other [ 60 , 81 ]. Additionally, in immunosuppressed patients, the prophylactic scheme with P+Sdz seems to reduce the rate of recurrences, however, more studies are needed [ 84 ].…”

Current Treatment of Toxoplasma Retinochoroiditis: An Evidence-Based Review

“…The first such approach historically was the application of laser photocoagulation directly on the lesion or in the immediately surrounding retina. For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37].…”

“…For example, in 1966, Spalter et al [37] presented a case series of 24 patients with a history of recurrent toxoplasma retinochoroiditis whose lesions were surrounded with laser photocoagulation. During a follow-up period ranging from 8 to 33 months there were only 2 recurrences (8%) and these were distant to the lesions treated [37]. However, in a case series of 35 patients that received laser photocoagulation around foci of Toxoplasma retinochoroiditis the recurrence rate was 53% in 5 years [38].…”

Laser Photocoagulation around the Foci of Toxoplasma Retinochoroiditis: A Descriptive Statistical Analysis of 35 Patients with Long-Term Follow-Up

“…As cysts are located in the neuroretina [4], they may be destroyed by the coagula tion process during the formation of the thermal damage. Rodriguez [19] in 1965 and Spatter et al [10] in 1966 first employed xenon lamp or argon laser photocoagulation in both active and inactive retinochoroiditis to shorten the in flammation period or to prevent recurrence. More recently, in 1989, Theodossiadis et al [12] studied the efficiency of argon laser photocoagulation in conjunction with medical treatment for active retinochoroiditis.…”