Property enhancement of dental composite prepared with an isosorbide-based photocurable compound by mixing with TEGDMA

Hydrophobically Modified Isosorbide Dimethacrylates as a Bisphenol-A (BPA)-Free Dental Filling Material

“…Isosorbide with its two-ring structure and hydroxyl functionality can resemble Bisphenol A, and as such, it is typically viewed as a potential BPA replacement [ 40 ]. In the work of Łukaszczyk et al, and Shin and coworkers, ISDGMA was proposed as a BisGMA replacement [ 27 , 28 ]. However, because of its hydrophilic nature, ISDGMA is reported to have higher water sorption relative to BisGMA.…”

“…It is made up of two cis -fused tetrahydrofuran rings, which are nearly planar, and contains two hydroxyls at positions 2 and 5, as shown in Figure 1 [ 20 , 21 ]. Isosorbide has found potential applications in the biomedical field, including aspirin prodrugs [ 22 , 23 ], substrates for human butyrylcholinesterase [ 24 ], tissue engineering scaffolds [ 25 , 26 ], and dental restorative materials [ 27 , 28 , 29 , 30 ].…”

“…Some of the studies on isosorbide for dental materials include the synthesis and evaluation of the BisGMA analogue, 1,4:3,6-dianhydro- d -sorbitol 2,5-bis(2-hydroxy-3-methacylolxypropoxy) (ISDGMA) as reported by Łukaszczyk et al, and Shin and coworkers [ 27 , 28 ]. Duarte et al, have studied the synthesis of an isosorbide urethane dimethacrylate (IS-UDMA) [ 29 ].…”

Synthesis of cubic spherosilicates for self-assembled organic–inorganic biohybrids based on functionalized methacrylates

“…HEMA is, among others, a precursor for the production of contact lenses, soft tissues, and vascular prostheses and can be used as a drug carrier. 35 EGDMA, in turn, is used to prepare bioinspired composites with interesting properties, for instance photocurable dental materials, 36 systems directed towards reduced oxidative stress and co-stimulatory factor expression in human monocytic cells, 37 porous hydrogel devices for the implantable delivery of insulin, 38 etc. Both materials, as polymers and copolymers, possess various advantages such as biocompatibility, hydrophilicity, and hardness similar to that observed for human bones and can be used as the filling of bone or tooth defects.…”

“…Both materials, as polymers and copolymers, possess various advantages such as biocompatibility, hydrophilicity, and hardness similar to that observed for human bones and can be used as the filling of bone or tooth defects. 36,39 From the chemical perspective, HEMA and EGDMA constitute valuable agents for cross-linking connections, because they contain hydroxyl -OH and terminal vinyl CQC groups. Such moieties are able to form not only linear chain copolymers but also more sophisticated structures.…”