Monte Carlo (MC) methods are well-known computational techniques widely used in different fields such as signal processing, communications and machine learning. An important class of MC methods is composed of importance sampling (IS) and its adaptive extensions, e.g., Adaptive Multiple IS (AMIS) and Population Monte Carlo (PMC). In this work, we introduce a novel adaptive and iterated importance sampler using a population of proposal densities. The proposed algorithm, named Adaptive Population Importance Sampling (APIS), provides a global estimation of the variables of interest iteratively, making use of all the samples previously generated. APIS combines a sophisticated scheme to build the IS estimators (based on the deterministic mixture approach) with a simple temporal adaptation (based on epochs). In this way, APIS is able to keep all the advantages of both AMIS and PMC while minimizing their drawbacks. Futhermore, the cloud of proposals is adapted in such a way that local features of the target density can be better taken into account compared to single global adaptation procedures. The result is a fast, simple, robust and high-performance algorithm applicable to a wide range of problems. Numerical results show the advantages of the proposed sampling scheme for a toy example and a localization problem in a wireless sensor network.