Prolonged Vitamin C Supplementation and Recovery from Demanding Exercise

Abstract

The aim of the present study was to investigate whether 2 weeks of vitamin C supplementation affects recovery from an unaccustomed bout of exercise. Sixteen male subjects were allocated to either a placebo (P; n = 8) or vitamin C group (VC; n = 8). The VC group consumed 200 mg of ascorbic acid twice a day, whereas the P group consumed identical capsules containing 200 mg of lactose. Subjects performed a prolonged (90-min) intermittent shuttle-running test 14 days after supplementation began. Post-exercise serum creatine kinase activities and myoglobin concentrations were unaffected by supplementation. However, vitamin C supplementation had modest beneficial effects on muscle soreness, muscle function, and plasma concentrations of malondialdehyde. Furthermore, although plasma interleukin-6 increased immediately after exercise in both groups, values in the VC group were lower than in the P group 2 hours after exercise (p < .05). These results suggest that prolonged vitamin C supplementation has some modest beneficial effects on recovery from unaccustomed exercise.

Aspectos atuais sobre estresse oxidativo, exercícios físicos e suplementação

“…From a non-habitual exercise bout, Thompson et al (42) evaluated the effect of two weeks of vitamin c supplementation over recovery. The supplemented group received two doses of 200 mg of vitamin C/day and, two weeks after the beginning of supplementation, the individuals were submitted to an intense and prolonged exercise protocol.…”

Delayed Onset Muscle Soreness and Mechanisms: Relation with Oxidative Stress: Review

“…[53][54][55][56][57] Bunun yanı sıra zorlu ve alışılmamış aktivitelerden sonra GKA'nın oluş-tuğu biliniyor olmasına rağmen, SR hasarı ve GKA arasında bir bağlantı olup olmadığı merak konusu olmuştur. Yapılan çalışmalar aşağıda verilen alt başlıklar altında incelenmiştir.…”

“…Thompson ve ark., 90 dakikalık aralıklı mekik koşu egzersizinde uzun süreli C vitamini kullanımının katılımcılarda orta seviyede pozitif etki sağladığını kaydetmişlerdir. 55 Benzer şe-kilde Kawanishi ve ark., kurkumin (zerdeçalın içinde bulunan antioksidan madde) ilavesinin, yokuş aşağı koşu egzersizlerinde meydana gelen kas hasarını ve oksidatif stresi azalttığını göstermişler-dir. 66 Eksantrik aktivitelerden iki hafta önce ve aktiviteden sonra dört gün boyunca uygulanan yüksek doz (3 g/gün) C vitamini takviyesinin kas hasarını azalttığı, antioksidan kapasiteyi artırdığı ve KK seviyesindeki artışı geciktirdiği saptanmış-tır.…”

Ascorbic Acid and Performance: A Review

“…The concentration of creatine kinase and myoglobin was not altered by supplementation. However, supplementation attenuated muscle pain, benefiting from the recovery of muscle function [16]. In another study, Thompson et al investigated the effect of post-exercise vitamin C supplementation on the recovery from the performance of an intense, prolonged and unusual workout.…”