Prokalsitonin, D-Dimer, Ferritin, Troponin ve Laktat Düzeylerinin COVID-19 Hastalığı ile İlişkisi

Şahin, Levent; Gür, Ali

doi:10.30565/medalanya.808806

Cited by 2 publications

(2 citation statements)

References 25 publications

(24 reference statements)

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“…Ferritin levels due to secondary hemophagocytic lymphohistiocytosis and cytokine storm syndrome seen in severe COVID-19 patients are much higher and indicate a poor prognosis [1]. In the study conducted by Sahin et al, it was determined that there was no statistically significant difference in ferritin levels between hospitalized and non-hospitalized patients [39]. Contrary to the literature, the ferritin level was high in hospitalized patients in our study.…”

Section: Discussioncontrasting

confidence: 83%

Clinical and laboratory factors associated with hospitalization and mortality in the COVID-19 pandemic

ATİLA¹,

BARIŞIK

2023

Family Practice and Palliative Care

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Introduction: This study aimed to investigate the relationship between MPV and disease prognosis in patients with COVID-19, the chronic diseases that affect the prognosis of COVID-19, and the laboratory data that can help diagnose this disease and provide information about the course of the disease during the treatment process. Methods: The study was conducted in a cross-sectional format. All participants gave written, informed consent to participate. A questionnaire consisting of two parts, including categorical (socio-demographic) data and laboratory data, was applied to people who had COVID-19 who applied to the internal medicine outpatient clinic of the hospital. The Pearson chi-squared test and Fisher exact test were used for comparing categorical variables. The Mann-Whitney U test, or Kruskal-Wallis test with Bonferroni post hoc comparisons, was used to compare numerical variables between the groups. All analyses were performed using the SPSS 25.0 (SPSS Inc., Chicago, IL, ‎USA) software package. Results: The participants' mean (±SD) age was 40.8±13.7 years (median: 40, range: 18 – 72). Almost half of the participants (48.0%, n=98) were male, the majority (76.0%, n=155) were married, and 24.0% (n=49) were single. Of the 204 patients, 28 (13.7%) were hospitalized, and five died (2.5%). Of the five patients who died, three had chronic lung disease, one had diabetes and chronic lung disease, and one had no chronic disease. Conclusion: Older age and the presence of chronic diseases are important factors affecting hospitalization in patients with COVID-19. LDH, CRP, and ferritin levels were high, and the mean platelet volume levels were significantly higher in hospitalized patients. Keywords: COVID -19, pandemics, prognosis of COVID -19

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Section: Discussioncontrasting

confidence: 83%

Clinical and laboratory factors associated with hospitalization and mortality in the COVID-19 pandemic

ATİLA¹,

BARIŞIK

2023

Family Practice and Palliative Care

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“…It has been shown that 14%-29% of patients with COVID-19 pneumonia required intensive care [ 8 ]. The disease has high mortality in the elderly and people with comorbidities; however, it can also cause severe clinical pictures in young people without comorbidities [ 9 ]. To prevent mortality, early detection of patients who require aggressive treatment is very important [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Laboratory Findings and Mortality in COVID-19 Patients Requiring Intensive Care

Bahçeci¹,

Mercantepe²,

Duran³

et al. 2023

Cureus

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Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows a wide clinical manifestation from asymptomatic infection to life-threatening respiratory failure. This study aimed to determine the relationship between the survival and demographic data, comorbidity status, and laboratory parameters of coronavirus disease 2019 (COVID-19) patients requiring intensive care.Material and methods: We retrospectively analyzed 236 patients requiring intensive care whose diagnosis was confirmed by the SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) test. The patients were divided into two groups in terms of survival. Demographic data; procalcitonin and C-reactive protein (CRP) levels; leukocyte, lymphocyte, and neutrophil counts in hemogram and neutrophil-tolymphocyte ratio (NLR) levels; and lower respiratory and blood cultures were examined, and the relationships between these parameters and survival were evaluated with hypothesis testing.Results: In the study, 156 (66.1%) males and 80 (33.9%) females, a total of 236 patients, were included. Sixty-seven (28.3%) surviving patients were determined as Group 1, and 169 (71.7%) deceased patients were determined as Group 2. A statistically significant difference was found between the groups in terms of mean age (p<0.001) and gender distribution (p=0.011). In laboratory parameters, a significant difference was observed between the groups in lymphocyte count (p=0.001), NLR (p<0.001), and procalcitonin levels (p<0.001). Although leukocyte (p=0.075), neutrophil (p=0.031), and CRP (p=0.112) levels were higher in Group 2, there was no statistical difference. Mortality was found to be higher in patients with comorbidity (p=0.012) or co-infection (p=0.002).Conclusion: High levels of neutrophil count, NLR, and procalcitonin; low lymphocyte count; the presence of comorbidity; and secondary bacterial infection were found to be associated with mortality in COVID-19 patients in the intensive care unit.

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Prokalsitonin, D-Dimer, Ferritin, Troponin ve Laktat Düzeylerinin COVID-19 Hastalığı ile İlişkisi

Cited by 2 publications

References 25 publications

Clinical and laboratory factors associated with hospitalization and mortality in the COVID-19 pandemic

Clinical and laboratory factors associated with hospitalization and mortality in the COVID-19 pandemic

The Relationship Between Laboratory Findings and Mortality in COVID-19 Patients Requiring Intensive Care

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