Abstract:Background
Pain is a common non-motor symptom of Parkinson`s disease (PD), however, its pathomechanism remains elusive.
Objective
We aimed to investigate the local gene expression of selected proinflammatory mediators in patients with PD and correlated our data with patients`pain phenotype.
Methods
We recruited 30 patients with PD and 30 healthy controls. Pain intensity of patients was assessed using the Numeric Rating Scale (NRS) and patients were stratified into PD pain (NRS≥4) and PD No Pain (NRS<4) … Show more
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