Progress Toward Regional Measles Elimination — Worldwide, 2000–2017

Dabbagh, Alya; Laws, Rebecca L.; Steulet, Claudia; Dumolard, Laure; Mulders, Mick N.; Kretsinger, Katrina; Alexander, James P.; Rota, Paul A.; Goodson, James L.

doi:10.15585/mmwr.mm6747a6

Cited by 144 publications

(134 citation statements)

References 2 publications

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“…In this region the situation is compounded by complacency in measles vaccination efforts, as well as nomadic lifestyles, and some apostolic religious communities that are reluctant to vaccinate. 17 Five of the six World Health Organization regions have reported increased cases, with The Americas, Eastern Mediterranean Region, and Europe experiencing the biggest increases in cases in 2017. 14,15 Socio-economic crises, such as the conflict in Syria, and other diseases (e.g.…”

Section: Reasons For Poor Vaccinationmentioning

confidence: 99%

“…14,15 Parental knowledge and attitudes also affect the vaccination of children. 17 Layperson and professional perceptions that vaccinations contain dangerous chemicals, or cause autism spectrum disorder, have negatively affected parental attitudes toward paediatric immunizations, particularly the vaccination against measles, mumps, and rubella. the Ebola virus outbreak in West Africa) which then dominate health care are additional causes.…”

Section: Reasons For Poor Vaccinationmentioning

confidence: 99%

“…9,46 This agent is considered a first-line intervention for the symptomatic treatment of seizures in patients with SSPE in countries such as Turkey and South Africa. 17 Early diagnosis is promoted by this adequate awareness and vigilance leading to investigations that are both specific and sensitive for the condition. The aetiology for the myoclonus is thought to be due to basal ganglia involvement of the virus, whose pathways are not governed by alterations in sodium channels.…”

Section: Symptomatic Treatmentmentioning

confidence: 99%

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Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions

Mekki

Eley

Hardie

et al. 2019

Develop Med Child Neuro

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Subacute sclerosing panencephalitis (SSPE) is a preventable condition reported in 6.5 to 11 per 100 000 cases of measles, and highest in children who contracted measles infection when they were less than 5 years of age. Children residing in areas with poor vaccination coverage and high prevalence of human immunodeficiency virus are at increased risk of developing SSPE. SSPE is life‐threatening in most affected children. This report documents current data relating to the clinical phenotype, epidemiology, and understanding of SSPE, inclusive of preventive interventions. While improvements in disease progression with immunomodulation may occur, overall there is no cure. Most therapies focus on supportive needs. Seizures and abnormal movements may respond to carbamazepine. Many countries advocate policies to enhance vaccination coverage. Effective preventive health care programmes, assurance of parental perceptions, and crisis support for unprecedented events obstructing effective primary health care are needed. Until measles is eradicated worldwide, children in all regions remain at risk. What this paper adds Measles contracted under 5 years of age has highest risk of developing subacute sclerosing panencephalitis (SSPE). Children with, or exposed to, human immunodeficiency virus infection, who contract measles may be at increased risk of SSPE.

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Section: Reasons For Poor Vaccinationmentioning

confidence: 99%

Section: Reasons For Poor Vaccinationmentioning

confidence: 99%

Section: Symptomatic Treatmentmentioning

confidence: 99%

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Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions

Mekki

Eley

Hardie

et al. 2019

Develop Med Child Neuro

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“…The global impact of vaccines was exemplified by measles where 21 million deaths have been averted between 2000 and 2017, leaving an estimated 110.000 annual measles deaths [1]. However, outbreaks have recently increased to a situation where many countries have too low vaccination coverage to control the disease.…”

Section: Tackling Emerging Infectious Diseasesmentioning

confidence: 99%

New paths for sustainable solutions to tackle global and emerging infectious threats

Holm¹

2020

Biologicals

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A B S T R A C TWith the dramatic background of a newly emerged virus (SARS-CoV-2) spreading around the world, Coronavirus and other infectious health threats for the human and animal populations were illustrated and debated in excellent presentations at the IABS meeting 26-28 of February 2020. Historical evidence of pandemics and lessons learned from recent epidemics or epizootics caused by many pathogens (e.g., Ebola, Zika, and African Swine Fever viruses) illustrated the overarching need for close international cooperation. New and old technologies in vaccine development and their use were presented, resulting in a call for greater interaction between the human and the veterinary fields in order to leverage the expertise and knowledge in both human and animal medicine. The One Health concept was also emphasized for eliminating the 59,000 fatal human rabies cases annually attributed to unvaccinated dogs. For preventable, infectious diseases commonly spreading in the poorer regions of the world, a new regulatory approach and governance structure was called for to give access to affordable vaccines. Vaccines were touted as one of the most successful health invention ever introduced; on a similar level to health improvements due to clean water. Human rabies causes approximately 59,000 deaths worldwide per https://doi.

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“…Vaccination is one of history's most successful public health interventions. Since 2000, vaccination campaigns against measles, which is highly contagious but preventable through the measles‐mumps‐rubella (MMR) vaccine, have reduced both the global incidence of the disease and measles deaths by 80 percent . However, progress toward measles elimination has slid backward in several previously well‐protected global regions.…”

Section: Policy and Politicsmentioning

confidence: 99%

Controlling Measles through Politics and Policy

Silverman¹

2019

Hastings Center Report

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Vaccination is one of history's most successful public health interventions. Since 2000, vaccination campaigns against measles, which is highly contagious but preventable through the measles‐mumps‐rubella (MMR) vaccine, have reduced both the global incidence of the disease and measles deaths by 80 percent. However, progress toward measles elimination has slid backward in several previously well‐protected global regions. With more communities below or at risk of falling below the 95 percent immunization rates required for herd immunity—due more and more to vaccine skepticism and declination rather than lack of access—many U.S. states and countries must reappraise their vaccination policies and programs.

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Progress Toward Regional Measles Elimination — Worldwide, 2000–2017

Cited by 144 publications

References 2 publications

Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions

Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions

New paths for sustainable solutions to tackle global and emerging infectious threats

Controlling Measles through Politics and Policy

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