Progress in the Development of New Vaccines Against Tuberculosis

Abstract

Due to the shortcomings of currently available BCG vaccines, new strategies have been considered for the development of alternative vaccines against tuberculosis. Many candidate vaccines are in the pipeline with an aim to replace BCG or boost the effect of BCG for prophylaxis. In addition, therapeutic applications are also considered. In this chapter, the current advances and approaches are explored to develop pre- and postexposure vaccines for tuberculosis.