Prognostic value of serum levels of soluble MICA (sMICA) in patients with prostate cancer

British Journal of Biomedical Science in 2018: what have we learned?

“…The authors conclude that sMICA is a promising marker for the presence, clinical severity and survival outcome in gastric cancer, possibly the first lab test to offer these clinical features. Liu et al [42] also measured sMICA, but in a cohort of 136 cases of prostate cancer. The principle finding was that sMICA was linked to clinical stage of the cancer.…”

“…Auto-immune Autoantigen [21] SEPP1 and SEP 15 Breast Carcinoma DNA mutation [35] Genes linked to E. coli virulence Kidney Infections DNA mutation [31] miR-146b Thyroid Papillary cancer DNA mutation [18] P53 and miR-34b/c Colon Autoimmune Autoantigen [43] sMICA Lung Carcinoma DNA mutation [38] H. pylori genes Stomach Infection H. pylori [46] CA125, ferritin Ovary Cancer DNA mutation [54] Neutrophil/lymphocyte ratio, CRP, LFTs Liver Infection Various microbes [22] miR-27a, miR-196a, miR-146a Breast Cancer DNA mutation [13] miR-126, miR-210 Heart Atherosclerosis, diabetes Thrombosis, hyperglycaemia [47] S100A4 (metastatin) Ovary Cancer DNA mutation [23] p21 Brain Meningioma DNA mutation [36] 16S-23s RNA region Not applicable Infection S. pneumoniae [42] sMICA, PSA Prostate Cancer DNA mutation [37] Bacterial identification Not applicable Infection P. aeruginosa, B. cenocepacia [39] Genes in H. pylori and parasites Bowel Infection DNA mutation [52] Genes in HPV Anus and genitals Infection DNA mutation [51] Haemostasis The eye Atherosclerosis, diabetes Thrombosis, Hyperglycaemia [48] CEA, CA19-9, cytokeratin-1, mucin-1 Colon Cancer DNA mutation [50] LFTs, platelets Liver Fibrosis Hepatitis B virus [21] Detection of foetal DNA Not applicable Chromosome trisomy DNA mutation [14] SNPs in KCNJ11 and SDF-1β Not applicable Diabetes DNA mutation [16] Serum relaxin-2, PSA Prostate Cancer DNA mutation [17] Serum prolidase and SNP in prolidase Ovary Polycystia Endocrine [55] SNP in IL28B Liver Infection Hepatitis C virus [15] SNPs in TLR4 Kidney, Arteries Diabetes DNA mutation [25] SNPs in GST Cervix Cancer DNA mutation [44] SNPs in TLR3, TLR7, TLR8 Liver Infection Hepatitis C virus [28] Pri-miR-124-1 and STAT3 Stomach Cancer DNA mutation [49] Monocyte/granulocyte to lymphocyte ratio Liver Cancer DNA mutation [56] Leptin, HOMA Liver Fibrosis He...…”