Prognostic instrument for survival outcome in melanoma patients: based on data from the population-based Swedish Melanoma Register

Abstract

Background: Several major analyses have identified a consistent set of independent

Benefits of initial CT staging before sentinel lymph node biopsy in patients with head and neck cutaneous melanoma

“…Other important prognostic factors for patients with melanoma are Breslow thickness, ulceration, dermal mitoses, and site of the primary tumor, as well as sex and age . This concurs with our findings that tumor thickness influenced the OS negatively.…”

“…[8][9][10] Other important prognostic factors for patients with melanoma are Breslow thickness, ulceration, dermal mitoses, and site of the primary tumor, as well as sex and age. 6,11 This concurs with our findings that tumor thickness influenced the OS negatively. In our cohort, the ulceration rate of the primary CMM was higher (34%) compared with Yancovitz et al 1 (25%).…”

Prognostic risk factors of first recurrence in patients with primary stages I–II cutaneous malignant melanoma – from the population‐based Swedish melanoma register

“…Our results show similar results as another Swedish population-based study. 6 This indicates that the important prognostic factors for recurrence and CMM death coincide. The large proportion of patients (114/173) with recurrence actually died from CMM.…”

“…3,4 Prognostic factors for death in localized invasive CMM are well documented in various studies across the world and also in studies using data from the population-based Swedish Melanoma Register (SMR). 3,[5][6][7][8][9] A worse prognosis in patients with localized primary CMM is related to increasing age, male sex, nodular histogenetic type, increasing tumour thickness, presence of tumour ulceration and also presence of mitoses in T1 CMM. 3,[5][6][7][8][9] However, few studies have used multivariable analyses to identify prognostic risk factors for first recurrence, including locoregional and distant metastases in stages I-II CMM patients.…”

“…3,[5][6][7][8][9] A worse prognosis in patients with localized primary CMM is related to increasing age, male sex, nodular histogenetic type, increasing tumour thickness, presence of tumour ulceration and also presence of mitoses in T1 CMM. 3,[5][6][7][8][9] However, few studies have used multivariable analyses to identify prognostic risk factors for first recurrence, including locoregional and distant metastases in stages I-II CMM patients. [10][11][12] Most previous studies have used selected hospital-based data, but only one has used population-based data.…”