Prognostic evaluation of ameloblastoma based on histologic and radiographic typing

Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor

“…In another study, the basal cell type showed the highest labeling index (24). Ueno et al (25) and Reichart et al (26) also stated that the high expression of PCNA in follicular ameloblastoma can explain its increased potential of recurrence, but in our study, the highest mean IP for PCNA was in acanthomatous ameloblastoma.…”

Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor

“…In another study, the basal cell type showed the highest labeling index (24). Ueno et al (25) and Reichart et al (26) also stated that the high expression of PCNA in follicular ameloblastoma can explain its increased potential of recurrence, but in our study, the highest mean IP for PCNA was in acanthomatous ameloblastoma.…”

A treatment algorythmn for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience

“…Treatment algorythmn for adult ameloblastomas 367 1996), there is also a significant relationship between recurrence and histological type (Wu et al, 1984;Ueno et al, 1989). In our study, most recurrences appear in follicular or follicular and cystic types: 42% of follicular types had recurrences and 51.6% of follicular and cystic type.…”

“…Indeed, the prognosis for the unicystic and peripheral ameloblastomas is so much better after a limited surgical procedure such as enucleation, enucleationecurettage and simple excision than it is for a solid or multicystic ameloblastomas. As for Ueno et al (1989), in conservative surgery, the recurrence rate of multicystic ameloblastomas was significantly higher in multilocular or soap bubble type (60.7%) than in the unilocular type (35%). A major factor is cancellous bone infiltration by ameloblastomas, but is largely confined by compact bone of the mandible inferior border and ascending ramus.…”

Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical

“…Some clinical parameters that could influence the rupture of the bone cortex, including size of the tumor and time of disease evolution, showed no significant correlation with bone cortical status, demonstrating that presence of myofibroblasts is an independent factor for bone infiltration. This is, to our knowledge, the first evidence that elevated myofibroblast may be useful to predict the prognosis of ameloblastoma patients, since rupture of the osseous cortical is one of the major prognostic factors of aggressiveness in patients with ameloblastomas [39,40]. Patients with cortical rupture show significantly higher recurrence rates than those with preserved cortical [41].…”

Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor

“…In another study, the basal cell type showed the highest labeling index (24). Ueno et al (25) and Reichart et al (26) also stated that the high expression of PCNA in follicular ameloblastoma can explain its increased potential of recurrence, but in our study, the highest mean IP for PCNA was in acanthomatous ameloblastoma.…”

A treatment algorythmn for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience

“…Treatment algorythmn for adult ameloblastomas 367 1996), there is also a significant relationship between recurrence and histological type (Wu et al, 1984;Ueno et al, 1989). In our study, most recurrences appear in follicular or follicular and cystic types: 42% of follicular types had recurrences and 51.6% of follicular and cystic type.…”

“…Indeed, the prognosis for the unicystic and peripheral ameloblastomas is so much better after a limited surgical procedure such as enucleation, enucleationecurettage and simple excision than it is for a solid or multicystic ameloblastomas. As for Ueno et al (1989), in conservative surgery, the recurrence rate of multicystic ameloblastomas was significantly higher in multilocular or soap bubble type (60.7%) than in the unilocular type (35%). A major factor is cancellous bone infiltration by ameloblastomas, but is largely confined by compact bone of the mandible inferior border and ascending ramus.…”

Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical

“…Some clinical parameters that could influence the rupture of the bone cortex, including size of the tumor and time of disease evolution, showed no significant correlation with bone cortical status, demonstrating that presence of myofibroblasts is an independent factor for bone infiltration. This is, to our knowledge, the first evidence that elevated myofibroblast may be useful to predict the prognosis of ameloblastoma patients, since rupture of the osseous cortical is one of the major prognostic factors of aggressiveness in patients with ameloblastomas [39,40]. Patients with cortical rupture show significantly higher recurrence rates than those with preserved cortical [41].…”

Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor

“…In another study, the basal cell type showed the highest labeling index (24). Ueno et al (25) and Reichart et al (26) also stated that the high expression of PCNA in follicular ameloblastoma can explain its increased potential of recurrence, but in our study, the highest mean IP for PCNA was in acanthomatous ameloblastoma.…”

A treatment algorythmn for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience

“…Treatment algorythmn for adult ameloblastomas 367 1996), there is also a significant relationship between recurrence and histological type (Wu et al, 1984;Ueno et al, 1989). In our study, most recurrences appear in follicular or follicular and cystic types: 42% of follicular types had recurrences and 51.6% of follicular and cystic type.…”

“…Indeed, the prognosis for the unicystic and peripheral ameloblastomas is so much better after a limited surgical procedure such as enucleation, enucleationecurettage and simple excision than it is for a solid or multicystic ameloblastomas. As for Ueno et al (1989), in conservative surgery, the recurrence rate of multicystic ameloblastomas was significantly higher in multilocular or soap bubble type (60.7%) than in the unilocular type (35%). A major factor is cancellous bone infiltration by ameloblastomas, but is largely confined by compact bone of the mandible inferior border and ascending ramus.…”

Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical

“…Some clinical parameters that could influence the rupture of the bone cortex, including size of the tumor and time of disease evolution, showed no significant correlation with bone cortical status, demonstrating that presence of myofibroblasts is an independent factor for bone infiltration. This is, to our knowledge, the first evidence that elevated myofibroblast may be useful to predict the prognosis of ameloblastoma patients, since rupture of the osseous cortical is one of the major prognostic factors of aggressiveness in patients with ameloblastomas [39,40]. Patients with cortical rupture show significantly higher recurrence rates than those with preserved cortical [41].…”