Abstract:• This study explored the clinical relevance of LSM5 gene in glioma diagnosis and treatment for the first time • LSM5 is overexpressed in lower-grade glioma (LGG) and glioblastoma multiforme (GBM) tissues • The promoter of LSM5 gene is differentially methylated in both LGG and GBM tissues • The expression of LSM5 correlates with the survival condition and immunophenotypes of glioma patients
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