2023
DOI: 10.3389/fpls.2023.1132555
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Production of secondary metabolites using tissue culture-based biotechnological applications

Abstract: Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food… Show more

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Cited by 60 publications
(23 citation statements)
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“…However, it is important to acknowledge that other approaches, such as AI-enabled drug discovery, vaccines, combination therapies, and phage, will all play a role in addressing the resistance crisis. Moreover, while this review has focused on microbially produced antimicrobials and approaches, other natural sources, such as molecules from plant species, have also been explored [ 171 , 172 , 173 , 174 ]. Medicinal chemistry efforts will also continue to be critical in extending the effectiveness of both current and new antibiotic leads.…”
Section: Discussionmentioning
confidence: 99%
“…However, it is important to acknowledge that other approaches, such as AI-enabled drug discovery, vaccines, combination therapies, and phage, will all play a role in addressing the resistance crisis. Moreover, while this review has focused on microbially produced antimicrobials and approaches, other natural sources, such as molecules from plant species, have also been explored [ 171 , 172 , 173 , 174 ]. Medicinal chemistry efforts will also continue to be critical in extending the effectiveness of both current and new antibiotic leads.…”
Section: Discussionmentioning
confidence: 99%
“…DPP contains a diverse array of secondary metabolites ( Table 1 ), including phenolic compounds [ 11 ], triterpenoids, sterols, and carotenoids. These organic compounds serve functions that extend beyond plant growth and reproduction, playing roles such as pest defense, pollinator attraction, and adaptation to environmental stress [ 32 , 33 ]. Consequently, these secondary metabolites possess a spectrum of bioactive properties that render them valuable for various human applications [ 34 ].…”
Section: Exploring Mechanisms: How Date Palm Pollen Composition Influ...mentioning
confidence: 99%
“…Moreover, the synthesis of nutritional and bioactive metabolites may be enhanced through elicitation approaches that stimulate stress responses to activate specific metabolic pathways to produce desired compounds. Such methods may include biotic (microorganisms) and abiotic (temperature, light, chemicals such as jasmonic acid and sodium chloride-NaCl) elicitors (Chandran et al 2020;Ozyigit et al 2023). For instance, excessive sodium chloride (NaCl) stress can be detrimental to plants, hindering growth and potentially leading to plant death.…”
Section: Introductionmentioning
confidence: 99%