Production of Phleichrome byCladosporium phleias Stimulated by Diketopiperadines ofEpichloe typhina

Seto, Yoshiki; Kogami, Yasunori; Shimanuki, Tadayuki; Takahashi, Kosaku; Matsuura, Hideyuki; Yoshihara, Toshio

doi:10.1271/bbb.69.1515

Cited by 21 publications

(21 citation statements)

References 15 publications

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“…Among the two inducers tested on PDA plates, cyclo-(L-Pro-LPhe) was a more potent inducer, which was also observed in the previous study using TLC bio-autography (11). The difference in VOL.…”

Section: Resultssupporting

confidence: 80%

“…To rapidly determine if phleichrome was present, the crude extract was analyzed using thin-layer chromatography (TLC) on silica gel with a resolving solution (CH 2 Cl 2 /MeOH ¼ 19:1, v/v) and purified phleichrome as a control, as described previously (10). In addition, the absorbance of the EtOAc extract was measured with a spectrophotometer at a wavelength of 474 nm by using a model DU530 spectrophotometer (Beckman, USA) (11). The concentration of phleichrome was calculated by reference to a regression line that was established with a known amount of purified phleichrome as a standard using a spectrophotometer at 474 nm.…”

Section: Quantification Of Phleichromementioning

confidence: 99%

“…Although these studies demonstrated that it was possible to prepare phleichrome from biological sources, a further increase in phleichrome production is required for the sustainable conversion of phleichrome to hypocrellins and the development of other effective derivatives. A previous study using TLC bio-autography revealed that two diketopiperazines from Epichloe typhina, an endophytic fungus of the timothy plant, stimulated the production of phleichrome from C. phlei (11). Therefore, it demonstrated the possibility of stimulation of phleichrome production.…”

mentioning

confidence: 97%

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Improved production of phleichrome from the phytopathogenic fungus Cladosporium phlei using synthetic inducers and photodynamic ROS production by phleichrome

Chae

et al. 2015

Journal of Bioscience and Bioengineering

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Section: Resultssupporting

confidence: 80%

Section: Quantification Of Phleichromementioning

confidence: 99%

mentioning

confidence: 97%

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Improved production of phleichrome from the phytopathogenic fungus Cladosporium phlei using synthetic inducers and photodynamic ROS production by phleichrome

Chae

et al. 2015

Journal of Bioscience and Bioengineering

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“…Despite the pathogenic nature of the fungus, Cladosporium sp. has also been reported to display antiviral, antifungal and antitumor activity (Seto et al, 2005;Wang et al, 2007;Hamayun et al, 2009;Zhang et al, 2009;de Medeiros et al, 2011). The present strain PE106, isolated from Ph.…”

Section: S T a P H Y L O C O C C U S Aureus B A Ci L L U S Subtilis Lmentioning

confidence: 90%

Isolation and evaluation of endophytic fungi with antimicrobial ability from Phyllostachys edulis

Shen

Zheng

Gao

et al. 2012

Bangladesh J Pharmacol

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“…Compound II was observed previously in beer [15]. It is produced by Lactobacillus plantarum and possess antifungal properties [16] and has also been observed in the fungus Epichloe tiphina [17]. Compound III has been detected by GC-MS in extract of Lucilia sericata larvae.…”

Section: Resultsmentioning

confidence: 79%

Amino acids and cyclic dipeptides in stinging nettle (Urtica dioica and U. urens) homeopathic matrix tinctures

et al. 2008

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Qualitative and quantitative contents of amino acids and N-containing substances isolated from lipophilic fractions of tinctures derived from both freshly collected plants and dried material of Urtica dioica L. and U. urens L. in accordance with homeopathic technology were studied using amino-acid analysis and GC-MS techniques. The amino-acid composition includes 18 compounds. The content of free amino acids amounted to 0.02 -0.21%; that of bound amino acids, 0.03 -0.29%, both being higher in tinctures obtained from freshly collected raw material. A comparison of the amino-acid contents before and after hydrolysis shows that amino acids are present in tinctures mostly in the free form. The analyses of tinctures showed the presence of pyrazine and pyrazole derivatives, including 4-ethyl-4,5-dihydro-5-propyl-1H-pyrazol-1-carboxyaldehyde isomers and hexahydropyrrolo[1, 2-a]pyrazin-1,4-dione derivatives with 3-alkyl and 3-phenylmethyl substituents in addition to 5,10-diethoxy-2,3,7,8-tetrahydro-1H,6H-dipyrrolo[1,2-a; 1¢,2¢-d]pyrazine. These biologically active compounds may contribute to the pharmacological effect of urtica-based phytopreparations. 650 0091-150X/08/4211-0650

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Production of Phleichrome byCladosporium phleias Stimulated by Diketopiperadines ofEpichloe typhina

Cited by 21 publications

References 15 publications

Improved production of phleichrome from the phytopathogenic fungus Cladosporium phlei using synthetic inducers and photodynamic ROS production by phleichrome

Improved production of phleichrome from the phytopathogenic fungus Cladosporium phlei using synthetic inducers and photodynamic ROS production by phleichrome

Isolation and evaluation of endophytic fungi with antimicrobial ability from <i>Phyllostachys edulis </i>

Amino acids and cyclic dipeptides in stinging nettle (Urtica dioica and U. urens) homeopathic matrix tinctures

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