Production of a bioactive lipid-based delivery system from ratfish liver oil by enzymatic glycerolysis

Corzo‐Martínez, Marta; Vázquez, Luís; Arranz-Martínez, Pablo; Menéndez, Nuria; Reglero, Guillermo; Torres, Carlos F.

doi:10.1016/j.fbp.2016.08.003

Cited by 20 publications

(6 citation statements)

References 42 publications

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“…In the same way, it is verified that the higher production of MAG and DAG was in this period, since such products are formed from the decomposition of the TAG. This was also observed by Corzo‐Martínez et al (2016) and Fiametti et al (2009) that the higher formation of MAG and DAG occurred within the first 120 min of reaction. It was also noted that the formation of MAG was much higher than that of DAG, but both stabilized at similar times, which indicates another sign that the amount of enzyme was sufficient in the process.…”

Section: Resultssupporting

confidence: 80%

Kinetic study of liquid lipase‐catalyzed glycerolysis of olive oil using Lipozyme TL 100L

Finco

Fiametti

Lobo

et al. 2022

J Americ Oil Chem Soc

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Monoacylglycerol (MAG) and diacylglycerol (DAG) are two natural components found in most edible oils and fats. Conventional synthesis of MAG and DAG is usually conducted by glycerolysis of triacylglycerol (TAG) at high temperatures (above 200°C) in the presence of an alkaline catalyst. In this work, the synthesis of MAG and DAG using enzymatic glycerolysis of olive oil was investigated using Tween 80 as surfactant, n‐butanol as co‐surfactant and the novel lipase in free/liquid formulation Lipozyme TL 100L as catalyst. Experimental design was used to evaluate the effect of enzyme load and reaction temperature on the feedstock conversion. Enzyme load and system temperature were significant variables in the statistical design and the best condition was found at 35°C, 7.5 vol% of Lipozyme TL 100L and glycerol to oil volumetric ratio of 2:1 with conversion of TAG at approximately 98% after 2 h of process. A mathematical model based on the Ping‐Pong Bi‐Bi mechanism was used to describe the reaction kinetics. The model adequately described the behavior of the system and can be a useful tool for the design of reactors in larger scales.

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Section: Resultssupporting

confidence: 80%

Kinetic study of liquid lipase‐catalyzed glycerolysis of olive oil using Lipozyme TL 100L

Finco

Fiametti

Lobo

et al. 2022

J Americ Oil Chem Soc

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“…This DG value is similar to that found by Ferreti et al [7], who after 8 h reached 54 % selectivity of DG in the conversion of the 70 % TG by glycerolysis reaction at 220°C using sunflower oil on MgO. Corzo-Martínez et al [83] also reported the production of MG and DG through glycerolysis of ratfisher liver oil catalyzed by the enzyme Novozyme 435. Maximum conversion was achieved after 24 h of reaction at 40°C, with 34 % MG and 3 % DG, approximately.…”

Section: Influence Of Catalyst Type and Contentsupporting

confidence: 87%

“…Corzo‐Martínez et al. also reported the production of MG and DG through glycerolysis of ratfisher liver oil catalyzed by the enzyme Novozyme 435. Maximum conversion was achieved after 24 h of reaction at 40 °C, with 34 % MG and 3 % DG, approximately.…”

Section: Resultsmentioning

confidence: 99%

Kinetics of Soybean Oil Hydrolysis on Niobium Catalysts

et al. 2020

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The catalytic hydrolysis of soybean oil was used as an alternative for the production of monoglycerides (MG) and diglycerides (DG). The reactions were conducted in a stainless-steel tubular reactor in the temperature range of 240-290°C, on niobium phosphate (NBP) and niobium oxide (NBO) as catalysts. In the hydrolysis reactions at 270°C, the maximum selectivities of the products of interest were obtained at 22 % MG and 48 % DG for the reaction with NBP, and 7 % MG and 33 % DG with NBO, for 59 % and 36 % of triglyceride conversion in 10 min, respectively. The proposed kinetic model presented a good fit of the theoretical model with the experimental data, showing that the previous hypotheses considered for the mechanism development are suitable for describing the kinetics of soybean oil hydrolysis.

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“…N435 was also used in the glycerolysis of ratfish liver oil to produce bioactive lipid carriers with potential selfemulsifying properties. 408 The same group reported later that the N435 catalyzed glycerolysis of ratfish liver oil allowed the process to be studied in a pilot plant, showing a catalyst halflife of 145 h (enzyme activity cannot be fully restored by hexane washings), and that glycerolysis of triacylglycerol was 1.5 times faster than that of diacylglycerol. 409 N435 was used for the glycerolysis of n-3 polyunsaturated fatty acid-rich ethyl oil as the first step in a new two-step process designed for the production of pure triacylglycerols enriched in n-3 polyunsaturated fatty acids.…”

Section: Food Technology: Glyceride Modifications and Productionmentioning

confidence: 99%