Abstract:Hemopressin is a nonapeptide derived from the α-1 chain of mammalian hemoglobin known for its hypotensive, analgesic and appetite suppressive effects. This peptide acts as a CB1 cannabinoid receptor inverse agonist or antagonist. Dysfunctions in the endocannabinoid system are associated with some pathologies and morbidity, such as obesity, neuropathic pain, depression, inflammation, Alzheimer and Parkinson diseases.This study was focused on the production and purification of synthetic and recombinant hemopress… Show more
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