Objectives. Prognosis for glioblastoma multiforme (GBM) has remained poor. Th ere is almost always recurrence postresection and adjuvant treatment, the majority of which is local. Several preclinical models exist that recapitulate the essential features of GBM. Th e majority of these models treat GBM in the neoadjuvant setting. Here, we describe an imageable intracranial surgical resection model of GBM in the rodent. Methods . We implanted 106 U87 luciferase-expressing GBM cells into the right hemisphere of 6…
scite is a Brooklyn-based startup that helps researchers better discover and evaluate scientific articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by researchers from dozens of countries and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.