We study experimentally nodal domains of wave functions (electric field distributions) lying in the regime of Breit-Wigner ergodicity in the chaotic microwave half-circular ray-splitting rough billiard. Using the rough billiard without ray-splitting properties we also study the wave functions lying in the regime of Shnirelman ergodicity. The wave functions Ψ N of the ray-splitting billiard were measured up to the level number N = 204. In the case of the rough billiard without ray-splitting properties, the wave functions were measured up to N = 435. We show that in the regime of Breit-Wigner ergodicity most of wave functions are delocalized in the n, l basis. In the regime of Shnirelman ergodicity wave functions are homogeneously distributed over the whole energy surface. For such wave functions, lying both in the regimes of Breit-Wigner and Shnirelman ergodicity, the dependence of the number of nodal domains ℵN on the level number N was found. We show that in the regimes of Breit-Wigner and Shnirelman ergodicity least squares fits of the experimental data reveal the numbers of nodal domains that in the asymptotic limit N → ∞ coincide within the error limits with the theoretical prediction ℵN /N 0.062. Finally, we demonstrate that the signed area distribution Σ A can be used as a useful criterion of quantum chaos.