Principles of the Urolithiasis Phytotherapy

Хохленкова, Н. В.; Buryak, Marina; Povrozina, O. V.; Kamina, T. V.

doi:10.5958/0974-360x.2019.00784.4

Cited by 4 publications

(1 citation statement)

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“…It is important to consider kidney stone disease as a systemic issue since it can cause cardiovascular damage, hypertension, insulin resistance, chronic kidney disease, and metabolic bone disease 8 . Due to extrinsic and endogenous variables that adversely affect the human body, urolithiasis has developed into endemic proportions in several geographical areas 9,10 . Genetic influences involving renal stones pathogenesis have also been identified 11 .…”

Section: Introductionmentioning

confidence: 99%

A Review on Kidney Stones & A Patient Satisfaction Survey of an Ayurvedic Brand to Treat Kidney Stones

Jain,

Kachare,

Gaikwad

et al. 2023

JOPCR

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Objective: Kidney stones or nephrolithiasis, is a common problem worldwide. About 12% of the Indian population is estimated to have kidney stones and out of which 50% may end up with loss of kidney functions. In the first part of this article the pathophysiology of kidney stone, its types, risk factors, signs, symptoms, diagnosis and therapy have been discussed. Furthermore, various therapeutic approaches for kidney stone management are also briefly renewed. Methods: The second part of this article discusses a herbal formulation Ren-Cit® successfully used to treat kidney stone, its usage, composition as well as the actions of each of its medicinal constituents. A survey of patients who used Ren-Cit® has been conducted. Finding: The analysis of this survey revealed that 98% of the patients were suffering from kidney stone. Out of these 78% of the patients had hypertension and diabetes. None of the participants observed any side effects from the usage of Ren-Cit®. A total of 76% patients got relief from kidney stone by using Ren-Cit®. Various types of kidney stones diagnosed in these patients had varied composition, viz.; calcium oxalate stone (52%), calcium phosphate stone (16%), uric acid stone (12%), struvite stone (12%) and cystine stone (8%). Novelty: Ren- Cit® ayurvedic formulation proved to be effective on a wide range and types of kidney Stones. Keywords: Kidney Stone; Urolithiasis; Calcium Oxalate; Uric Acid Stone; Calcium Phosphate; Ren-Cit®

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Section: Introductionmentioning

confidence: 99%

A Review on Kidney Stones & A Patient Satisfaction Survey of an Ayurvedic Brand to Treat Kidney Stones

Jain,

Kachare,

Gaikwad

et al. 2023

JOPCR

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A Systematic Review on Chemical Composition and Biological Activities of cedar Oils and Extracts

Chauiyakh,

El Fahime,

Aarabi

et al. 2023

RJPT

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The valorization of aromatic and medicinal plants is a vital research axis in the field of valorization and optimization of natural resources. Cedar is one of the most sought-after plants in the world due to the quality of its wood and its richness in bioactive molecules that can be used in the pharmaceutical, cosmetic, and perfumery industries. Using keywords such as: Cedrusatlantica Manetti, Cedrusbrevifolia Henry, Cedrus deodara London,Cedruslibani London and Cedrusbrevifolia Henry, articles were collected from international scientific databases. The analysis of the abstracts of these articles by computer tools such as Zotero, Excel, and Nvivo allowed us to conclude that the chemical composition of cedar varies from one species to another and from one part of the plant to another and according to the harvesting environment. However, it is generally characterized by the dominance of terpenes. The latter is known to have antimicrobial properties, which explains the effectiveness of the oils and extracts of this plant against fungi and bacteria such as helicobacter pylori, Gram-positive and Gram-negative bacteria, and important anticancer power.

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Evaluation of the Antilithiasic activity, Phospho-ammoniaco-magnésien of the aqueous extract of Fraxinus excelsior (L.)

Ghenaiet

Boutefnouchet

Lekouaghet

et al. 2022

AJRC

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The formation of urinary stones is a serious clinical problem in the world, the struvite of which is one of the characteristic components of urolithiasis of infectious origin. The objective of this study is to evaluate the in vitro litholytic and inhibitory effects of the leaf aqueous extract of Fraxinus excelsior L plant on the crystallization of struvite. The plant is commonly used in traditional Algerian medicine.A characterization method of Fraxinus excelsior L plant was first performed to determine the total phenolic and flavonoid compounds of Fraxinus excelsior L leaf aqueous extract. Struvite crystals prepared with two different processes had subsequently undergone an inhibition assay by supplementing Aqueous Extract with varying concentrations. In the first process, struvite was biologically crystallized in a synthetic urine in the presence of Proteus mirabilis during 24 hours of incubation period. This was followed by the addition of Aqueous Extract, the effect of which was evaluated after 1-hour. In the second process, struvite crystals were chemically synthesized for 30 minutes in the presence of aqueous extract. These two processes allow to assess, respectively, the litholytic effect of aqueous extract on the previously formed struvite crystals and the inhibitory effect of the crystallization of struvite. These various tests of crystallization and inhibition of struvite crystals were conducted by Polarized Light Microscopy (PLM) and Fourier Transform Infrared (FTIR) Spectroscopy. The results reveal that this Aqueous Extract contains an estimated total phenolic content of 60.92 ± 0.94 mg gallic acid equivalent (GAE)/g of extract and a total flavonoid content of 19.32 ± 0.75 mg quercetin equivalent (QE)/g of extract. The in vitro struvite crystals dissolution testing revealed a significant litholytic effect. Also, the struvite crystallization inhibition testing showed that it exerted a significant inhibitory effect observed with polarized light.The effect of this extract is evident against struvite crystals with a conclusive litholytic and inhibitory potential. The present results open up significant preventive management prospects for this type of lithiasis.

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Principles of the Urolithiasis Phytotherapy

Cited by 4 publications

References 0 publications

A Review on Kidney Stones & A Patient Satisfaction Survey of an Ayurvedic Brand to Treat Kidney Stones

A Review on Kidney Stones & A Patient Satisfaction Survey of an Ayurvedic Brand to Treat Kidney Stones

A Systematic Review on Chemical Composition and Biological Activities of cedar Oils and Extracts

Evaluation of the Antilithiasic activity, Phospho-ammoniaco-magnésien of the aqueous extract of Fraxinus excelsior (L.)

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