Abstract:Any numerical series can be decomposed into principal components using singular spectral analysis. We have recently proposed a new analysis method ‒ PCA-Seq, which allows calculating numerical principal components for a sequence of elements of any type. In particular, the sequence may be composed of nucleotide base pairs or amino acid residues. Two questions inevitably arise about interpretation of the obtained principal components and about the assessment of their reliability. For interpretation of the symbol… Show more
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