Primary Squamous Cell Carcinoma of the Sternum

Garach, Niharika Rajan; Kammar, Praveen; Deshpande, Akshay; Pandey, Vinita; Mehta, Sanket

doi:10.1016/j.athoracsur.2020.05.030

Cited by 1 publication

(1 citation statement)

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“…While osteosarcomas may be treated with neoadjuvant chemotherapy, chondrosarcomas are unresponsive to radiation or chemotherapy, therefore complete surgical resection is their only chance for cure. Other infrequent primary tumors such as squamous cell carcinoma have also been described ( 5 ).…”

Section: Indications For Sternal Resection ( Table 1 ...mentioning

confidence: 99%

Sternal resection and reconstruction: a review

Aranda,

Gomez,

Fuentes

et al. 2024

J Thorac Dis

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Sternal resection and reconstruction is a rare but sometimes challenging procedure due to its profound anatomical and functional implications. For these reasons, an adequate preoperative evaluation is crucial in each patient, especially when we are faced with malignant lesions that sometimes require extensive radical resections, thus demanding an integrated reconstructive strategy that allows stabilizing the chest wall, protecting the underlying mediastinum and minimize resulting deformity. The large number of available reconstruction techniques and the lack of quality studies for their analysis mean that sternal reconstruction depends to a great extent on the consensus of experts or, more frequently, on the simple preference of each surgical team. This article aims to provide an overview of sternal resection and reconstruction. Indications for partial versus total or subtotal sternectomy are suggested and their surgical and oncological outcomes are presented. The use of rigid or semi-rigid prostheses is an ongoing debate, although recent functional data advise reserving rigid reconstructions for extensive defects. Sternectomy for primary tumors or local tumor involvement has a good prognosis with an overall survival of 5 and 10 years: 67% and 58%, respectively, provided that a radical resection with free surgical margins is performed. Breast cancer is the most common secondary sternal tumor, and surgery can offer 5-year overall survival ranging from 20% to 50% provided an R0 resection is achieved, although radical surgery does not appear to decrease rates. of recurrence. Metastases of origin other than the breast give the worst results (less than 40% at 36 months and 0% at 5 years) and although the data available on these cases are limited, the radicality of the resection does not seem to modify the survival or recurrence rates, so a conservative approach is probably more appropriate.

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Section: Indications For Sternal Resection ( Table 1 ...mentioning

confidence: 99%