Primary Myoepithelioma of the Testis - A Case Report -

Abstract

Myoepitheliomas are well-established to occur in the salivary glands, but they have also been described in the breast, upper aerodigestive tract, skin, and soft tissues. We report here on a unique case of primary myoepithelioma that occurred in the right testis of a 28-year-old man. The tumor was entirely confined to the testis and it was clearly separated from the epididymis. Histopathology revealed mixed architectural patterns in which the reticular areas merged into the chondromyxoid stroma. The tumor cells, which were focally immunoreactive to pancytokeratin and S-100 protein, were round to ovoid and spindly arranged in cords, strands, and fascicles. They showed mild nuclear pleomorphism, sparse mitotic figures and a low Ki-67 proliferative index. There was no ductal differentiation in the tumor. To the best of our knowledge, there has been only one case report of a primary testicular myoepithelioma in the English medical literature.

Imprint Cytology of Soft Tissue Myoepithelioma: A Case Study

“…The tumor presents as a painless or painful mass in the dermis, subcutis, or deep soft tissue 3,4. While most myoepitheliomas are of salivary gland origin, they have been reported in the soft tissue, retroperitoneum,3 lung,5 and testis 6. The histogenesis of myoepithelial tumors arising in soft tissue is unknown.…”

Primary cutaneous myoepithelial carcinoma: a case report and review of the literature

“…Myoepitheliomas proliferate from specialized contractile myoepithelial cells, which are present in the salivary glands, breast, respiratory tract, and skin . Myoepithelial tumours have been reported in the breast , tracheobronchial structures , soft tissue , larynx , cranial dura , sinonasal cavity , palate , retroperitoneum , vulva , testis , bone , and skin . These are often found in the salivary glands, although they only represent 1.5% of all salivary gland tumours .…”

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